Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 5/20 | 0.41 |
| ▸ | HTR7 | P34969 | 5/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.39 |
| ▸ | HTR2C | P28335 | 3/20 | 0.39 |
| ▸ | HRH1 | P35367 | 2/20 | 0.39 |
| ▸ | DRD3 | P35462 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | CCR3 | P51677 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 3/20 | 0.39 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053666 | 0.97 | OPRM1 (0.43) | OPRM1OPRD1OPRK1P2RX7HTR1A | |
| SCHEMBL9053460 | 0.90 | P2RX7 (0.47) | OPRM1OPRD1OPRK1P2RX7HTR1A | |
| SCHEMBL9054400 | 0.82 | DRD2 (0.42) | OPRM1OPRD1OPRK1HTR1AHTR7 | |
| SCHEMBL9053981 | 0.80 | KDM4E (0.42) | OPRM1OPRD1OPRK1P2RX7DRD2 | |
| SCHEMBL8316876 | 0.77 | OPRD1 (0.53) | OPRM1OPRD1OPRK1P2RX7HTR1A | |
| SCHEMBL9054642 | 0.74 | SIGMAR1 (0.39) | HTR1AHTR7DRD2HTR2CDRD3 | |
| SCHEMBL9054788 | 0.73 | DRD3 (0.55) | OPRK1P2RX7HTR1AHTR7DRD2 | |
| SCHEMBL13904314 | 0.73 | SIGMAR1 (0.59) | OPRM1OPRD1OPRK1P2RX7SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9055462 | 0.72 | DRD3 (0.54) | OPRK1P2RX7HTR1AHTR7DRD2 | |
| SCHEMBL9053846 | 0.72 | HPGDS (0.56) | DRD2DRD3DRD4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706522-A1 | TETRAZOLE DERIVATIVES HAVING ANTIHISTAMINIC AND ANTIALLERGIC ACTIVITY | SUMITOMO METAL INDUSTRIES, LTD. (JP) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001350-A1 | TETRAZOLE DERIVATIVES HAVING ANTIHISTAMINIC AND ANTIALLERGIC ACTIVITY | SUMITOMO METAL INDUSTRIES, LTD. (JP) | 1995-01-12 | — | — | WO | disclosed |