Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPBWR1 | P48145 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | NOS1 | P29475 | 1/20 | 0.47 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.47 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.47 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.47 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6257538 | 0.87 | CYP19A1 (0.54) | NPBWR1KDM4EMAPTPOLBMEN1 | |
| SCHEMBL28993262 | 0.85 | KDM4E (0.52) | NPBWR1KDM4EMAPTPOLBMEN1 | |
| SCHEMBL1122279 | 0.79 | RIPK1 (0.60) | NPBWR1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL1630724 | 0.78 | MAPT (0.51) | NPBWR1KDM4EMAPTPOLBMEN1 | |
| SCHEMBL9183096 | 0.77 | CA12 (0.54) | KDM4EMAPTPOLBMEN1KMT2A | |
| SCHEMBL19335080 | 0.76 | ALDH1A1 (0.48) | NPBWR1KDM4EMAPTPOLBMEN1 | |
| SCHEMBL28784277 | 0.76 | MAPT (0.42) | KDM4EMAPTMEN1KMT2ALMNA | |
| SCHEMBL7807147 | 0.75 | KDM4E (0.55) | NPBWR1KDM4EMAPTPOLBMEN1 | |
| SCHEMBL17141271 | 0.75 | MTNR1A (0.48) | MAPTPOLBMEN1KMT2ALMNA | |
| SCHEMBL5150341 | 0.75 | MAPT (0.51) | NPBWR1MAPTPOLBMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004906-A1 | COMPOUNDS FOR THE TREATMENT OF RESTENOSIS | THE WELLCOME FOUNDATION LIMITED (GB) | 1996-02-22 | — | — | WO | disclosed |