Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.51 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.51 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.51 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | NOS1 | P29475 | 1/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | NPBWR1 | P48145 | 3/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30917347 | 0.86 | CYP19A1 (0.60) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL317330 | 0.86 | CYP19A1 (0.60) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL397170 | 0.81 | ALDH1A1 (0.56) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL4969287 | 0.79 | MAPT (0.51) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL5150341 | 0.79 | MAPT (0.51) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL4885975 | 0.78 | MAPT (0.47) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL9053698 | 0.78 | NPBWR1 (0.52) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL10117949 | 0.77 | ALDH1A1 (0.55) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL4427396 | 0.76 | GRIA1 (0.58) | MAPTGRIA1GRIA2GRIA3GRIA4 | |
| SCHEMBL397992 | 0.76 | MAPT (0.49) | MAPTGRIA1GRIA2GRIA3GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116782896-A | Nitrifying galectin derivatives and their use for modulating 5-HT2A receptors and treating psychotic disorders | 恩维瑞克生物科学加拿大公司 | 2023-09-19 | — | — | CN | disclosed |
| EP-4208446-A1 | NITRATED PSILOCYBIN DERIVATIVES AND USE THEREOF FOR MODULATING 5-HT2A RECEPTOR AND FOR TREATING A PSYCHIATRIC DISORDER | Enveric Biosciences Canada Inc. (CA) | 2023-07-12 | — | — | EP | disclosed |
| US-20230040398-A1 | NITRATED PSILOCYBIN DERIVATIVES AND METHODS OF USING | Enveric Biosciences Canada Inc. (CA) | 2023-02-09 | — | — | US | disclosed |
| WO-2022047583-A1 | NITRATED PSILOCYBIN DERIVATIVES AND USE THEREOF FOR MODULATING 5-HT2A RECEPTOR AND FOR TREATING A PSYCHIATRIC DISORDER | MAGICMED INDUSTRIES INC. (CA) | 2022-03-10 | — | — | WO | disclosed |
| EP-3318557-A2 | QUINOLONE COMPOUND | Otsuka Pharmaceutical Co., Ltd. (JP) | 2018-05-09 | — | — | EP | disclosed |
| EP-1979314-B1 | INDOLE SULFONAMIDE MODULATORS OF PROGESTERONE RECEPTORS | LILLY CO ELI (US) | 2013-01-09 | — | — | EP | disclosed |
| CN-101374808-B | Indole sulfonamide modulators of progesterone receptors | LILLY CO ELI | 2011-05-25 | — | — | CN | disclosed |
| US-7932284-B2 | Indole sulfonamide modulators of progesterone receptors | ELI LILLY AND COMPANY (US) | 2011-04-26 | — | — | US | disclosed |
| US-20100197938-A1 | Process for producing indole compoud | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2010-08-05 | — | — | US | disclosed |
| US-20090069400-A1 | Indole Sulfonamide Modulators of Progesterone Receptors | ELI LILLY AND COMPANY | 2009-03-12 | — | — | US | disclosed |
| CN-101374808-A | Indole sulfonamide modulators of progesterone receptors | LILLY CO ELI (US) | 2009-02-25 | — | — | CN | disclosed |
| US-20070083053-A1 | Process for producing indole compound | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2007-04-12 | — | — | US | disclosed |
| EP-1276721-A2 | METHYLATION OF INDOLE COMPOUNDS USING DIMETHYL CARBONATE | F. HOFFMANN-LA ROCHE AG (CH) | 2003-01-22 | — | — | EP | disclosed |
| WO-2001081305-A2 | METHYLATION OF INDOLE COMPOUNDS USING DIMETHY CARBONATE | F. HOFFMANN-LA ROCHE AG (CH) | 2001-11-01 | — | — | WO | disclosed |
| WO-1999028297-A1 | SUBSTITUTED INDOLES, HAVING A THROMBIN INHIBITING EFFECT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-06-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090069400-A1 | Indole Sulfonamide Modulators of Progesterone Receptors | PGR, NPSR1, PRLHR | MAPT 4285/4885GRIA1 329/4885GRIA2 481/4885 |
| US-20100197938-A1 | Process for producing indole compoud | IDO1, IDO2, NOS2 | MAPT 2936/4885GRIA1 2536/4885GRIA2 1673/4885 |
| US-20230040398-A1 | NITRATED PSILOCYBIN DERIVATIVES AND METHODS OF USING | PNMT, CNR2, NOS2 | MAPT 2200/4885GRIA1 2189/4885GRIA2 2500/4885 |
| US-20070083053-A1 | Process for producing indole compound | IDO2, IDO1, TDO2 | MAPT 3200/4885GRIA1 2827/4885GRIA2 1794/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.