Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | NOS1 | P29475 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 2/20 | 0.40 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.40 |
| ▸ | GRIA3 | P42263 | 2/20 | 0.40 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MMP2 | P08253 | 1/20 | 0.37 |
| ▸ | MMP9 | P14780 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28761405 | 0.90 | CYP19A1 (0.46) | MAPTLMNAKCNJ1ALDH1A1NOS1 | |
| SCHEMBL28787309 | 0.78 | MTNR1A (0.36) | MAPTALDH1A1KDM4EPKMTDP1 | |
| SCHEMBL28658782 | 0.78 | DAO (0.42) | KDM4E | |
| SCHEMBL27550869 | 0.78 | DAO (0.42) | ALOX15 | |
| SCHEMBL28072258 | 0.78 | MAPT (0.43) | MAPTALDH1A1CYP3A4KDM4EMEN1 | |
| SCHEMBL28993262 | 0.77 | KDM4E (0.52) | MAPTLMNAKCNJ1ALDH1A1CYP3A4 | |
| SCHEMBL5171836 | 0.77 | ALDH1A1 (0.43) | MAPTLMNAKCNJ1ALDH1A1CYP3A4 | |
| SCHEMBL28341208 | 0.76 | KCNJ1 (0.39) | MAPTLMNAKCNJ1ALDH1A1CYP3A4 | |
| SCHEMBL9053698 | 0.76 | NPBWR1 (0.52) | MAPTLMNAKCNJ1ALDH1A1CYP3A4 | |
| SCHEMBL27488329 | 0.76 | LOXL2 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101790313-A | Compound (I) | SMITHKLINE BEECHAM CORP | 2010-07-28 | — | — | CN | disclosed |