Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLOD2 | O00469 | 2/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 2/20 | 0.59 |
| ▸ | APP | P05067 | 1/20 | 0.59 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.59 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.59 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.57 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.57 |
| ▸ | F7 | P08709 | 1/20 | 0.57 |
| ▸ | F3 | P13726 | 1/20 | 0.57 |
| ▸ | SARM1 | Q6SZW1 | 1/20 | 0.57 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.57 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.57 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.57 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.57 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.57 |
| ▸ | SIRT4 | Q9Y6E7 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29626189 | 1.00 | PLOD2 (0.65) | PLOD2ALDH1A1GAAAPPHCAR3 | |
| Bromide SCHEMBL27962027 | 0.98 | PLOD2 (0.62) | PLOD2ALDH1A1GAAAPPHCAR3 | |
| SCHEMBL30696670 | 0.87 | PLOD2 (0.59) | PLOD2ALDH1A1GAAAPPHCAR3 | |
| SCHEMBL11809006 | 0.85 | PLOD2 (0.67) | PLOD2ALDH1A1GAAAPPHCAR3 | |
| SCHEMBL552724 | 0.85 | PLOD2 (0.61) | PLOD2ALDH1A1GAAAPPHCAR3 | |
| SCHEMBL29350386 | 0.85 | PLOD2 (0.61) | PLOD2ALDH1A1GAAAPPHCAR3 | |
| SCHEMBL7075878 | 0.83 | PLOD2 (0.69) | PLOD2ALDH1A1GAAAPPHCAR3 | |
| SCHEMBL10320930 | 0.83 | PLOD2 (0.89) | PLOD2ALDH1A1GAAAPPHCAR3 | |
| SCHEMBL29554726 | 0.83 | PLOD2 (0.89) | PLOD2ALDH1A1GAAAPPHCAR3 | |
| SCHEMBL31231125 | 0.82 | PLOD2 (0.57) | PLOD2ALDH1A1GAAAPPHCAR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 378 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119375400-A | Sample pretreatment method for detecting CD38 enzyme activity in whole blood sample and method for detecting blood CD38 enzyme activity by high performance liquid chromatography | 北京医院 | 2025-01-28 | — | — | CN | claimed |
| CN-106103426-B | 8- (piperazine -1- base) -1,2,3,4- tetrahydro-isoquinoline derivative | 爱杜西亚药品有限公司 | 2019-03-19 | — | — | CN | claimed |
| EP-1915149-B1 | NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS | AETERNA ZENTARIS GMBH (DE) | 2018-10-10 | — | — | EP | claimed |
| CN-107250133-A | Hydroxyalkyl piperazine derivatives as CXCR3 receptor modulators | 爱杜西亚药品有限公司 | 2017-10-13 | — | — | CN | claimed |
| CN-104093715-B | 4-(benzoimidazol-2-yl)-thiazole compounds and related aza derivatives | 埃科特莱茵药品有限公司 | 2017-04-26 | — | — | CN | claimed |
| CN-106103426-A | 8 (piperazine 1 base) 1,2,3,4 tetrahydro isoquinoline derivatives | 埃科特莱茵药品有限公司 | 2016-11-09 | — | — | CN | claimed |
| CN-104093715-A | 4-(benzoimidazol-2-yl)-thiazole compounds and related aza derivatives | ACTELION PHARMACEUTICALS LTD | 2014-10-08 | — | — | CN | claimed |
| US-8710089-B2 | Triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors | ZENTARIS GMBH (DE) | 2014-04-29 | — | — | US | claimed |
| US-20100331343-A1 | NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS | ZENTARIS GMBH (DE) | 2010-12-30 | — | — | US | claimed |
| US-20090042905-A1 | TRIAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS | AETERNA ZENTARIS GMBH (DE) | 2009-02-12 | — | — | US | claimed |
| EP-1958631-A1 | Novel triazole derivatives as ligands of G-protein coupled receptors | AEterna Zentaris GmbH (DE) | 2008-08-20 | — | — | EP | claimed |
| EP-1915149-A2 | NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS | AEterna Zentaris GmbH (DE) | 2008-04-30 | — | — | EP | claimed |
| US-20070208061-A2 | NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS | ZENTARIS GMBH (DE) | 2007-09-06 | — | — | US | claimed |
| EP-1757290-A1 | Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors | Zentaris GmbH (DE) | 2007-02-28 | — | — | EP | claimed |
| WO-2007020013-A2 | NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS | ÆTERNA ZENTARIS GMBH (DE) | 2007-02-22 | — | — | WO | claimed |
| US-20070037857-A1 | Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors | ZENTARIS GMBH (DE) | 2007-02-15 | — | — | US | claimed |
| WO-2007012980-A1 | TOBACCO WITH AN INCREASED LEVEL OF NATURAL TAR DILUTENTS | PHILIP MORRIS PRODUCTS S.A. (CH) | 2007-02-01 | — | — | WO | claimed |
| US-20060283469-A1 | Tobacco with an increased level of natural tar diluents | PHILIP MORRIS USA INC. (US) | 2006-12-21 | — | — | US | claimed |
| EP-0159769-B1 | ELECTROCHEMICAL OXIDATION OF PYRIDINE BASES | REILLY INDUSTRIES, INC. (US) | 1991-03-27 | — | — | EP | claimed |
| US-4873362-A | REACTING AN ACYLOXYACETALDEHYDE WITH AN ALDEHYDE USING AN AMINE AND ACID CATALYST SYSTEM | BASF AKTIENGESELLSCHAFT (DE) | 1989-10-10 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208061-A2 | NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS | GIPR, GHSR, GPR119 | PLOD2 2569/4885ALDH1A1 3459/4885GAA 1604/4885 |
| US-20100331343-A1 | NOVEL TRIAZOLE DERIVATIVES AS GHRELIN ANALOGUE LIGANDS OF GROWTH HORMONE SECRETAGOGUE RECEPTORS | GIPR, GHSR, GPR119 | PLOD2 2569/4885ALDH1A1 3459/4885GAA 1604/4885 |
| US-20070037857-A1 | Novel triazole derivatives as ghrelin analogue ligands of growth hormone secretagogue receptors | GIPR, GHSR, GPR119 | PLOD2 2569/4885ALDH1A1 3459/4885GAA 1604/4885 |
| US-20090042905-A1 | TRIAZOLE DERIVATIVES AS LIGANDS OF G-PROTEIN COUPLED RECEPTORS | GPR3, GRK3, GPR88 | PLOD2 4608/4885ALDH1A1 2149/4885GAA 3696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.