Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 11/20 | 0.55 |
| ▸ | DRD2 | P14416 | 4/20 | 0.50 |
| ▸ | DRD3 | P35462 | 4/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MLNR | O43193 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9052509 | 0.96 | P2RX7 (0.57) | P2RX7DRD2DRD3HDAC4HDAC1 | |
| SCHEMBL9052502 | 0.95 | DRD2 (0.54) | P2RX7DRD2DRD3HDAC4HDAC1 | |
| SCHEMBL9054788 | 0.93 | DRD3 (0.55) | P2RX7DRD2DRD3DRD4CHRM2 | |
| Hydrochloric Acid SCHEMBL9055462 | 0.92 | DRD3 (0.54) | P2RX7DRD2DRD3DRD4MEN1 | |
| SCHEMBL9053711 | 0.88 | ACHE (0.56) | P2RX7DRD2DRD3DRD4CHRM1 | |
| SCHEMBL9054481 | 0.84 | NPSR1 (0.53) | P2RX7MEN1LMNAOPRM1KMT2A | |
| SCHEMBL347141 | 0.79 | HPGDS (0.67) | DRD2DRD3DRD4MLNRNR1I2 | |
| SCHEMBL9053460 | 0.75 | P2RX7 (0.47) | P2RX7DRD2DRD3DRD4LMNA | |
| SCHEMBL18089568 | 0.74 | HRH3 (0.42) | HRH1 | |
| SCHEMBL9055677 | 0.74 | HPGDS (0.60) | DRD2DRD3DRD4MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706522-A1 | TETRAZOLE DERIVATIVES HAVING ANTIHISTAMINIC AND ANTIALLERGIC ACTIVITY | SUMITOMO METAL INDUSTRIES, LTD. (JP) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001350-A1 | TETRAZOLE DERIVATIVES HAVING ANTIHISTAMINIC AND ANTIALLERGIC ACTIVITY | SUMITOMO METAL INDUSTRIES, LTD. (JP) | 1995-01-12 | — | — | WO | disclosed |