Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 6/20 | 0.54 |
| ▸ | DRD3 | P35462 | 6/20 | 0.54 |
| ▸ | P2RX7 | Q99572 | 8/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9053324 | 0.95 | P2RX7 (0.55) | DRD2DRD3P2RX7ADRA1BHDAC4 | |
| SCHEMBL9052509 | 0.92 | P2RX7 (0.57) | DRD2DRD3P2RX7ADRA1BHDAC4 | |
| SCHEMBL9054788 | 0.89 | DRD3 (0.55) | DRD2DRD3P2RX7DRD4 | |
| Hydrochloric Acid SCHEMBL9055462 | 0.88 | DRD3 (0.54) | DRD2DRD3P2RX7DRD4 | |
| SCHEMBL9053711 | 0.83 | ACHE (0.56) | DRD2DRD3P2RX7ADRA1BDRD4 | |
| SCHEMBL9054481 | 0.80 | NPSR1 (0.53) | P2RX7 | |
| SCHEMBL18089568 | 0.77 | HRH3 (0.42) | — | |
| SCHEMBL10760285 | 0.76 | DRD2 (0.64) | DRD2DRD3P2RX7ADRA1B | |
| SCHEMBL347141 | 0.75 | HPGDS (0.67) | DRD2DRD3ADRA1BDRD4 | |
| SCHEMBL9836728 | 0.75 | DRD2 (0.67) | DRD2DRD3P2RX7ADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706522-A1 | TETRAZOLE DERIVATIVES HAVING ANTIHISTAMINIC AND ANTIALLERGIC ACTIVITY | SUMITOMO METAL INDUSTRIES, LTD. (JP) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001350-A1 | TETRAZOLE DERIVATIVES HAVING ANTIHISTAMINIC AND ANTIALLERGIC ACTIVITY | SUMITOMO METAL INDUSTRIES, LTD. (JP) | 1995-01-12 | — | — | WO | disclosed |