Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 4/20 | 0.73 |
| ▸ | GAA | P10253 | 1/20 | 0.61 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.50 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.49 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.49 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.49 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 3/20 | 0.47 |
| ▸ | LOX | P28300 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 4/20 | 0.47 |
| ▸ | MMP1 | P03956 | 3/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | MMP9 | P14780 | 1/20 | 0.47 |
| ▸ | MMP8 | P22894 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | PKLR | P30613 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL930312 | 0.92 | PKM (0.58) | PKMGAAFFAR4MMP13MMP1 | |
| SCHEMBL14486413 | 0.85 | PKM (1.00) | PKMGAARAPGEF4HSD11B1CA2 | |
| SCHEMBL13074716 | 0.85 | PKM (1.00) | PKMGAARAPGEF4HSD11B1CA2 | |
| SCHEMBL835692 | 0.85 | PKM (1.00) | PKMGAARAPGEF4HSD11B1CA2 | |
| SCHEMBL21573778 | 0.85 | PKM (0.68) | PKMGAARAPGEF4HSD11B1TAS1R3 | |
| SCHEMBL4613497 | 0.85 | HTR6 (0.54) | PKMGAAFFAR4MMP2MMP9 | |
| SCHEMBL21540974 | 0.85 | PTGS2 (0.51) | PKMGAALOXFFAR4MMP13 | |
| SCHEMBL178454 | 0.83 | CA1 (0.61) | GAATAS1R3TAS1R1TAS1R2CA2 | |
| SCHEMBL26268 | 0.83 | PKM (0.65) | PKMGAARAPGEF4FFAR4MMP13 | |
| SCHEMBL19557330 | 0.83 | MAPT (0.54) | PKMGAAFFAR4MMP13MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8277261-A | — | — | None | — | — | JP | disclosed |
| US-20220017645-A1 | CHARGE-BEARING CYCLODEXTRIN POLYMERIC MATERIALS AND METHODS OF MAKING AND USING SAME | AVENUE GLOBAL DISLOCATION OPPORTUNITIES FUND, L.P. AND AVENUE GLOBAL OPPORTUNITIES MASTER FUND, L.P. | 2022-01-20 | — | — | US | disclosed |
| US-11155646-B2 | Charge-bearing cyclodextrin polymeric materials and methods of making and using same | CYCLOPURE, INC. (US) | 2021-10-26 | — | — | US | disclosed |
| US-20210163631-A1 | CHARGE-BEARING CYCLODEXTRIN POLYMERIC MATERIALS AND METHODS OF MAKING AND USING SAME | AVENUE GLOBAL DISLOCATION OPPORTUNITIES FUND, L.P. AND AVENUE GLOBAL OPPORTUNITIES MASTER FUND, L.P. | 2021-06-03 | — | — | US | disclosed |
| US-11001645-B2 | Charge-bearing cyclodextrin polymeric materials and methods of making and using same | CYCLOPURE, INC. (US) | 2021-05-11 | — | — | US | disclosed |
| US-20200262936-A1 | CHARGE-BEARING CYCLODEXTRIN POLYMERIC MATERIALS AND METHODS OF MAKING AND USING SAME | AVENUE GLOBAL DISLOCATION OPPORTUNITIES FUND, L.P. AND AVENUE GLOBAL OPPORTUNITIES MASTER FUND, L.P. | 2020-08-20 | — | — | US | disclosed |
| EP-3350149-B1 | [(2-ETHOXY-5-TRANS-1-PROPEN-1-YL)-PHENOXYL]-TERMINATED COMPOUNDS | EVONIK DEGUSSA GMBH (DE) | 2019-11-20 | — | — | EP | disclosed |
| US-20160271089-A1 | METHODS AND COMPOSITIONS FOR ORAL DELIVERY OF FTS | KADMON CORPORATION, LLC (US) | 2016-09-22 | — | — | US | disclosed |
| JP-H08277261-A | ASYMMETRIC 4,4'-DIALKYLOXYDIPHENYLSULFONE COMPOUND, ITS PRODUCTION AND PRODUCTION OF 4-ALKYLOXY-4'-HYDROXYDIPHENYLSULFONE COMPOUND USING THE COMPOUND | YOSHITOMI PHARMACEUT IND LTD | 1996-10-22 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160271089-A1 | METHODS AND COMPOSITIONS FOR ORAL DELIVERY OF FTS | HRAS, KRAS, KSR2 | PKM 4650/4885GAA 1330/4885RAPGEF4 490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.