Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.61 |
| ▸ | CA2 | P00918 | 2/20 | 0.61 |
| ▸ | CA7 | P43166 | 2/20 | 0.61 |
| ▸ | CA9 | Q16790 | 2/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.52 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.52 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.52 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21202067 | 0.93 | ESR2 (0.54) | CA1CA2CA7CA9CA12 | |
| SCHEMBL23917764 | 0.93 | LTA4H (0.56) | CA1CA2CA7CA9CA12 | |
| SCHEMBL125543 | 0.88 | ALDH1A3 (0.64) | ALDH1A1LMNAALDH1A3KMT2APARP10 | |
| Anisole SCHEMBL28836834 | 0.87 | CA4 (0.67) | CA1CA2CA7CA9CA12 | |
| SCHEMBL22507191 | 0.87 | ACACB (0.53) | CA1CA2CA7CA9CA12 | |
| SCHEMBL23917965 | 0.87 | PTGIR (0.50) | CA1CA2CA7CA9CA12 | |
| SCHEMBL12552792 | 0.85 | ALDH1A1 (0.46) | CA1CA2CA7CA9CA12 | |
| SCHEMBL21423323 | 0.85 | CYP1A2 (0.47) | CA1CA2CA7CA9CA12 | |
| SCHEMBL5512005 | 0.83 | CA1 (0.61) | CA1CA2CA7CA9CA12 | |
| SCHEMBL9054589 | 0.83 | PKM (0.73) | CA1CA2ALDH1A3TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0365328-B1 | Pyridine derivatives | ZENECA LTD (GB) | 1996-04-03 | — | — | EP | claimed |
| US-5053415-A | Antiischemic, antiinflammatory, antiarthritic agents, cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-01 | — | — | US | claimed |
| EP-0365328-A2 | Pyridine derivatives | ZENECA LIMITED (GB) | 1990-04-25 | — | — | EP | claimed |
| US-12037453-B2 | Aromatic polyethers containing a biosourced furan diol | ROQUETTE FRERES (FR) | 2024-07-16 | — | — | US | disclosed |
| US-20230276701-A1 | ORGANIC COMPOUND AND ORGANIC LIGHT EMISSION DEVICE | OSAKA UNIVERSITY (JP) | 2023-08-31 | — | — | US | disclosed |
| US-20230276701-A1 | ORGANIC COMPOUND AND ORGANIC LIGHT EMISSION DEVICE | OSAKA UNIVERSITY (JP) | 2023-08-31 | — | — | US | disclosed |
| US-20210317265-A1 | AROMATIC POLYETHERS CONTAINING A BIOSOURCED FURAN DIOL | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2021-10-14 | — | — | US | disclosed |
| US-10752626-B2 | Iso-citrate dehydrogenase (IDH) inhibitor | SHANGHAI METON PHARMACEUTICAL CO., LTD (CN) | 2020-08-25 | — | — | US | disclosed |
| US-20190256511-A1 | ISO-CITRATE DEHYDROGENASE (IDH) INHIBITOR | ZHEJIANG METON PHARMACEUTICAL CO., LTD (CN) | 2019-08-22 | — | — | US | disclosed |
| US-10342796-B2 | Acrylanilide derivative, preparation method, and applications thereof in pharmacy | ANCUREALL PHARMACEUTICAL (SHANGHAI) CO., LTD. (CN) | 2019-07-09 | — | — | US | disclosed |
| CN-109843968-A | Resin composition for fiber-reinforced composite material and fiber-reinforced composite material using same | 日铁化学材料株式会社 | 2019-06-04 | — | — | CN | disclosed |
| EP-0389162-B1 | 2,5,6,7-Tetranor-4,8-inter-m-phenylene PGI2 derivatives | TORAY INDUSTRIES (JP) | 1993-12-08 | — | — | EP | disclosed |
| US-5086071-A | Improved chemical stability and ppotent in vivo | TORAY INDUSTRIES, INC. (JP) | 1992-02-04 | — | — | US | disclosed |
| US-5053415-A | Antiischemic, antiinflammatory, antiarthritic agents, cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-01 | — | — | US | disclosed |
| EP-0232776-B1 | 2,5,6,7-TETRANOR-4,8-INTER-M-PHENYLENE PGI2 DERIVATIVES | TORAY INDUSTRIES, INC. (JP) | 1990-10-24 | — | — | EP | disclosed |
| EP-0365678-A1 | 2,5,6,7-TETRANOR-4,8-INTER-m-PHENYLENE PGI 2 DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND USE THEREOF | TORAY INDUSTRIES, INC. (JP) | 1990-05-02 | — | — | EP | disclosed |
| EP-0365328-A2 | Pyridine derivatives | ZENECA LIMITED (GB) | 1990-04-25 | — | — | EP | disclosed |
| US-4775692-A | ANTILIPEMIC, ANTICOAGULANT, HYPOTENSIVE, ANTISECRETORY AND ANTIULCER AGENT | TORAY INDUSTRIES, INC. (JP) | 1988-10-04 | — | — | US | disclosed |
| US-4698338-A | ANTIBIOTICS | ELI LILLY AND COMPANY (US) | 1987-10-06 | — | — | US | disclosed |
| EP-0233780-A2 | O-substituted oximino cephalosporins | ELI LILLY AND COMPANY (US) | 1987-08-26 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10342796-B2 | Acrylanilide derivative, preparation method, and applications thereof in pharmacy | EGFR, ABL1, CSNK1A1 | CA1 2885/4885CA2 397/4885CA7 535/4885 |
| US-20190256511-A1 | ISO-CITRATE DEHYDROGENASE (IDH) INHIBITOR | IDH3A, IDH2, IDH1 | CA1 932/4885CA2 302/4885CA7 696/4885 |
| US-20230276701-A1 | ORGANIC COMPOUND AND ORGANIC LIGHT EMISSION DEVICE | ESR1, ECE1, ESYT1 | CA1 3763/4885CA2 4265/4885CA7 4159/4885 |
| US-10752626-B2 | Iso-citrate dehydrogenase (IDH) inhibitor | IDH3A, IDH2, IDH1 | CA1 932/4885CA2 302/4885CA7 696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.