Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | HRH1 | P35367 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1739273 | 0.89 | TSHR (0.44) | TSHRALDH1A1TDP1CHRM1AKR1A1 | |
| SCHEMBL27998122 | 0.83 | ALDH1A1 (0.36) | TSHRALDH1A1TDP1HSD17B10ALOX15 | |
| SCHEMBL905474 | 0.82 | TSHR (0.40) | TSHRALDH1A1TDP1CHRM1AKR1A1 | |
| SCHEMBL905472 | 0.82 | TSHR (0.40) | TSHRALDH1A1TDP1CHRM1AKR1A1 | |
| SCHEMBL17559956 | 0.79 | GPR84 (0.38) | TSHRALDH1A1TDP1CHRM1AKR1A1 | |
| SCHEMBL13906520 | 0.78 | ALDH1A1 (0.44) | TSHRALDH1A1TDP1CHRM1HSD17B10 | |
| SCHEMBL3686281 | 0.78 | TSHR (0.42) | TSHRTDP1CHRM1AKR1A1CHRM3 | |
| SCHEMBL28003567 | 0.78 | HDAC7 (0.42) | TSHRALDH1A1TDP1CHRM1AKR1A1 | |
| SCHEMBL29645274 | 0.77 | ALOX15 (0.57) | TSHRALDH1A1TDP1ALOX15 | |
| SCHEMBL15512626 | 0.77 | LMNA (0.50) | TSHRALDH1A1TDP1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2278014-A2 | Method for producing alcohol and carboxylic acid having optical activity | API Corporation (JP) | 2011-01-26 | — | — | EP | disclosed |
| EP-2270178-A2 | Method for producing alcohol and carboxylic acid having optical activity | API Corporation (JP) | 2011-01-05 | — | — | EP | disclosed |
| US-20080233621-A1 | Method For Producing Alcohol and Carboxylic Acid Having Optical Activity | API CORPORATION (JP) | 2008-09-25 | — | — | US | disclosed |