Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.54 |
| ▸ | MMP7 | P09237 | 1/20 | 0.54 |
| ▸ | MMP9 | P14780 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | CNR2 | P34972 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.50 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.50 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.50 |
| ▸ | TAOK1 | Q7L7X3 | 2/20 | 0.49 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.49 |
| ▸ | GUSB | P08236 | 1/20 | 0.49 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9054219 | 0.90 | MMP2 (0.53) | MMP2MMP7MMP9MMP13FAAH | |
| SCHEMBL9196809 | 0.86 | MMP2 (0.56) | MMP2MMP7MMP9MMP13FAAH | |
| SCHEMBL9396390 | 0.86 | MMP2 (0.56) | MMP2MMP7MMP9MMP13FAAH | |
| SCHEMBL9196805 | 0.86 | MMP2 (0.56) | MMP2MMP7MMP9MMP13FAAH | |
| SCHEMBL9202511 | 0.82 | CNR1 (0.56) | MMP2MMP7MMP9MMP13FAAH | |
| SCHEMBL9202517 | 0.82 | CNR1 (0.56) | MMP2MMP7MMP9MMP13FAAH | |
| SCHEMBL5898184 | 0.82 | ADAM17 (0.56) | MMP2MMP7MMP9MMP13RAB9A | |
| SCHEMBL1477287 | 0.80 | SLC6A5 (0.65) | FAAHCNR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9201097 | 0.79 | FAAH (0.53) | FAAHCNR2NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9201093 | 0.79 | FAAH (0.53) | FAAHCNR2NPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996005729-A1 | VICINAL-SUBSTITUTED CARBOCYCLIC COMPOUNDS AS THERAPEUTIC AGENTS | ELI LILLY AND COMPANY (US) | 1996-02-29 | — | — | WO | disclosed |
| US-5432198-A | Enzyme inhibitors | SPHINX PHARMACEUTICALS CORPORATION (US) | 1995-07-11 | — | — | US | disclosed |