Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | YES1 | P07947 | 1/20 | 0.54 |
| ▸ | KDR | P35968 | 1/20 | 0.54 |
| ▸ | JAK3 | P52333 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 5/20 | 0.51 |
| ▸ | FNTA | P49354 | 1/20 | 0.51 |
| ▸ | FNTB | P49356 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9054478 | 0.89 | YES1 (0.68) | HTR2CALDH1A1YES1KDRJAK3 | |
| SCHEMBL18229435 | 0.89 | LMNA (0.59) | HTR2CALDH1A1YES1KDRJAK3 | |
| SCHEMBL8804260 | 0.88 | YES1 (0.69) | HTR2CALDH1A1YES1KDRJAK3 | |
| SCHEMBL28374626 | 0.83 | ALDH1A1 (0.62) | HTR2CALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL26391933 | 0.83 | HTR2C (1.00) | HTR2CALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL8804773 | 0.82 | PTPN5 (0.64) | ALDH1A1LMNAMAPTSMN1; SMN2MAPK1 | |
| SCHEMBL3854264 | 0.80 | TUBB4A (0.67) | HTR2CALDH1A1LMNAMAPTSMN1; SMN2 | |
| SCHEMBL9055521 | 0.80 | YES1 (0.81) | HTR2CALDH1A1YES1KDRJAK3 | |
| SCHEMBL9055555 | 0.80 | GAA (0.65) | HTR2CALDH1A1LMNAMAPK1GAA | |
| SCHEMBL8416372 | 0.80 | YES1 (0.67) | ALDH1A1YES1KDRJAK3FNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0775131-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA Medica Aktiengesellschaft (DE) | 1997-05-28 | — | — | EP | disclosed |
| WO-1996004266-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1996-02-15 | — | — | WO | disclosed |