Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | LAP3 | P28838 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 6/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4172471 | 0.85 | KDM4E (0.43) | CYP2C9CYP2C19MAPT | |
| SCHEMBL4167588 | 0.84 | FDPS (0.44) | LMNAFDPS | |
| SCHEMBL4156218 | 0.84 | CHRNB2 (0.41) | CYP2C9CYP2C19 | |
| SCHEMBL3187016 | 0.82 | ALDH1A1 (0.43) | CYP2C9CYP2C19LMNAMAPT | |
| SCHEMBL4169306 | 0.82 | MAPT (0.48) | LMNAMAPT | |
| SCHEMBL5198822 | 0.81 | NPSR1 (0.39) | CYP2C9CYP2C19LMNAMAPT | |
| SCHEMBL8727337 | 0.80 | TAAR1 (0.41) | — | |
| SCHEMBL1407856 | 0.78 | TRPA1 (0.42) | ANPEPLAP3 | |
| SCHEMBL11416970 | 0.78 | ANPEP (0.49) | CYP2C9CYP2C19ANPEPLAP3MTNR1A | |
| SCHEMBL19619723 | 0.78 | ANPEP (0.49) | CYP2C9CYP2C19ANPEPLAP3MTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004234-A1 | ARYLOXY ANDARYCTHIO PROPANOLAMINE DERIVATIVES USEFUL AS B3-ADRENORECEPTOR AGONISTS AND ANTAGONS OF THE B1 AND B2 ADRENORECEPTORS AND PHARMACEUTICAL COMPOSITION THEREOF | SMITHKLINE BEECHAM PLC (GB) | 1996-02-15 | — | — | WO | disclosed |