Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 6/20 | 0.52 |
| ▸ | HTT | P42858 | 4/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.52 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.52 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056446 | 0.84 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4EGAAHTT | |
| SCHEMBL18029755 | 0.77 | POLB (0.63) | ALDH1A1MAPTKDM4EGAAHTT | |
| SCHEMBL8809532 | 0.76 | PKM (0.48) | ALDH1A1MAPTKDM4EGAAHTT | |
| SCHEMBL3607553 | 0.75 | RAB9A (0.55) | ALDH1A1MAPTKDM4EGAAHTT | |
| SCHEMBL23240069 | 0.75 | ALDH1A1 (0.59) | ALDH1A1MAPTKDM4EGAAHTT | |
| Hydrochloric Acid SCHEMBL8808042 | 0.75 | PKM (0.47) | ALDH1A1MAPTKDM4EGAAHTT | |
| SCHEMBL9517392 | 0.75 | ALDH1A1 (0.52) | ALDH1A1MAPTKDM4EGAAHTT | |
| SCHEMBL8810278 | 0.74 | POLB (0.49) | ALDH1A1MAPTKDM4EGAAHTT | |
| SCHEMBL8533974 | 0.74 | HTT (0.53) | ALDH1A1MAPTKDM4EGAAHTT | |
| SCHEMBL6560675 | 0.73 | ALDH1A1 (0.50) | ALDH1A1MAPTKDM4EGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |