Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 7/20 | 0.35 |
| ▸ | AKT1 | P31749 | 2/20 | 0.35 |
| ▸ | AKT2 | P31751 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.35 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | HTR2B | P41595 | 2/20 | 0.34 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.34 |
| ▸ | RPS6KA4 | O75676 | 1/20 | 0.34 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.34 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.34 |
| ▸ | RPS6KA1 | Q15418 | 1/20 | 0.34 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.34 |
| ▸ | RPS6KA6 | Q9UK32 | 1/20 | 0.34 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056833 | 1.00 | ACHE (0.40) | ACHEMCHR1DGAT1FFAR4RPS6KB1 | |
| SCHEMBL9053167 | 0.81 | ACHE (0.41) | ACHEMCHR1DGAT1FFAR4HTR2C | |
| SCHEMBL9053164 | 0.81 | ACHE (0.41) | ACHEMCHR1DGAT1FFAR4HTR2C | |
| SCHEMBL9056444 | 0.79 | HPGDS (0.41) | ACHEDGAT1FFAR4HTR2CHTR2B | |
| SCHEMBL9056435 | 0.79 | HPGDS (0.41) | ACHEDGAT1FFAR4HTR2CHTR2B | |
| Hydrochloric Acid SCHEMBL9057145 | 0.78 | HPGDS (0.40) | ACHEDGAT1FFAR4HTR2CHTR2B | |
| SCHEMBL9058092 | 0.76 | DGAT1 (0.41) | ACHEMCHR1DGAT1FFAR4HTR2C | |
| SCHEMBL9058103 | 0.76 | DGAT1 (0.41) | ACHEMCHR1DGAT1FFAR4HTR2C | |
| Hydrochloric Acid SCHEMBL9057748 | 0.75 | RPS6KB1 (0.37) | ACHEDGAT1FFAR4RPS6KB1AKT1 | |
| SCHEMBL9053271 | 0.69 | HTR2C (0.38) | DGAT1FFAR4HTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004271-A1 | CONDENSED AZEPINE DERIVATIVES, DRUGS CONTAINING THESE COMPOUNDS AND METHODS FOR PREPARING THEM | DR. KARL THOMAE GMBH (DE) | 1996-02-15 | — | — | WO | disclosed |