Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.41 |
| ▸ | HCRTR2 | O43614 | 7/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RHOA | P61586 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8807120 | 0.84 | GAA (0.48) | GAANPSR1MAPTALDH1A1ROCK2 | |
| SCHEMBL9056291 | 0.83 | ROCK2 (0.43) | SMN1; SMN2GAANPSR1MAPTNTRK1 | |
| SCHEMBL8809317 | 0.83 | ROCK2 (0.43) | SMN1; SMN2GAANPSR1MAPTNTRK1 | |
| SCHEMBL8807169 | 0.82 | ROCK2 (0.42) | SMN1; SMN2GAANPSR1MAPTNTRK1 | |
| SCHEMBL8810019 | 0.82 | ROCK2 (0.43) | LMNASMN1; SMN2GAANPSR1MAPT | |
| SCHEMBL8809258 | 0.81 | ROCK2 (0.57) | GAANPSR1NTRK1ROCK2 | |
| SCHEMBL9057529 | 0.80 | WNT1 (0.44) | GAANPSR1MAPTABL1ROCK2 | |
| SCHEMBL8809549 | 0.80 | GAA (0.44) | LMNASMN1; SMN2GAANPSR1MAPT | |
| SCHEMBL9059369 | 0.79 | GAA (0.49) | GAANPSR1MAPTALDH1A1 | |
| SCHEMBL8809295 | 0.79 | ALDH1A1 (0.46) | LMNASMN1; SMN2GAANPSR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996010559-A1 | UREA DERIVATIVES AND THEIR USE AS ACAT-INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-04-11 | — | — | WO | disclosed |