Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | CCR2 | P41597 | 3/20 | 0.38 |
| ▸ | MGLL | Q99685 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | PDE6D | O43924 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9056381 | 0.81 | CCR2 (0.46) | MTNR1AMTNR1BCCR2GPR35PPARG | |
| SCHEMBL8388013 | 0.79 | HDAC8 (0.48) | CYP3A4 | |
| SCHEMBL203679 | 0.73 | ALDH1A1 (0.61) | MGLLCYP3A4NPSR1PKMSMN1; SMN2 | |
| SCHEMBL8802614 | 0.73 | ENPP2 (0.39) | MGLLCYP3A4NPSR1PKMSMN1; SMN2 | |
| SCHEMBL8387427 | 0.72 | TSHR (0.48) | CYP3A4NPSR1PKMSMN1; SMN2PPARG | |
| Hydrochloric Acid SCHEMBL25259767 | 0.72 | ALDH1A1 (0.59) | MGLLCYP3A4NPSR1PKMSMN1; SMN2 | |
| SCHEMBL27609022 | 0.70 | CYP3A4 (0.49) | MGLLCYP3A4NPSR1PKMSMN1; SMN2 | |
| Phenylacetic Acid SCHEMBL11667819 | 0.69 | PAM (0.59) | MGLLCYP3A4NPSR1PKMSMN1; SMN2 | |
| SCHEMBL17386357 | 0.69 | CYP3A4 (0.50) | CYP3A4NPSR1PKMSMN1; SMN2ALDH1A1 | |
| SCHEMBL2584456 | 0.67 | HCAR2 (0.48) | CYP3A4NPSR1PKMSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1166169-A | Heterocyclic compounds, useful as allosteric effectors at muscarinic receptors | SANKYO CO (JP) | 1997-11-26 | — | — | CN | disclosed |
| WO-1996003377-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY, LIMITED (JP) | 1996-02-08 | — | — | WO | disclosed |