Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 5/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.46 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.46 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.43 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.40 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.40 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9057255 | 0.81 | MTNR1A (0.41) | CCR2MTNR1AMTNR1BPTGDR2KDM4E | |
| SCHEMBL8387304 | 0.73 | HDAC8 (0.55) | KDM4EALDH1A1HPGDHSD17B10AKR1B1 | |
| SCHEMBL8386934 | 0.73 | KDM4E (0.65) | PTGDR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL7151151 | 0.73 | CCR2 (0.52) | CCR2PTGDR2KDM4EPPARGTSHR | |
| SCHEMBL8388141 | 0.70 | ALDH1A1 (0.53) | PTGDR2KDM4EALDH1A1HPGDHSD17B10 | |
| SCHEMBL16421404 | 0.70 | MIF (0.65) | ALDH1A1 | |
| SCHEMBL27323515 | 0.69 | CCR2 (0.46) | CCR2KDM4EALDH1A1HPGDGPR35 | |
| SCHEMBL9373764 | 0.69 | CCR2 (0.57) | CCR2KDM4EALDH1A1HPGDPPARG | |
| SCHEMBL7554153 | 0.69 | CCR2 (0.57) | CCR2ALDH1A1PPARGAGTR1AGTR2 | |
| SCHEMBL5696415 | 0.68 | AKR1B1 (0.81) | AKR1B1PLA2G10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996003377-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY, LIMITED (JP) | 1996-02-08 | — | — | WO | disclosed |