SCHEMBL9058295

SCHEMBL9058295

COC1=C(C(C)=O)Cc2ccc(OC)cc2O1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.41
CA2 P00918 3/20 0.41
CA5A P35218 2/20 0.41
CA12 O43570 2/20 0.41
CA9 Q16790 2/20 0.41
HPGD P15428 2/20 0.41
CYP3A4 P08684 1/20 0.41
MAPK1 P28482 1/20 0.41
KDM4E B2RXH2 1/20 0.40
MTNR1A P48039 2/20 0.39
METAP1 P53582 2/20 0.38
DRD2 P14416 1/20 0.38
DRD1 P21728 1/20 0.38
DRD4 P21917 1/20 0.38
DRD5 P21918 1/20 0.38
DRD3 P35462 1/20 0.38
NOTUM Q6P988 1/20 0.38
MTNR1B P49286 1/20 0.37
HIF1A Q16665 1/20 0.37
GABRA1 P14867 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9058193 0.88 MTNR1A (0.44) ALDH1A1CA2CA12CA9HPGD
SCHEMBL9058487 0.82 MAOA (0.44) ALDH1A1CA12CA9HPGDMAPK1
SCHEMBL22650934 0.81 CA2 (0.51) ALDH1A1CA2CA5ACA12CA9
SCHEMBL9058219 0.77 CA12 (0.39) CA12CA9MAPK1GAAMAOB
SCHEMBL31525565 0.74 CA12 (0.54) ALDH1A1CA2CA5ACA12CA9
SCHEMBL14495775 0.74 CA12 (0.54) ALDH1A1CA2CA5ACA12CA9
SCHEMBL8869451 0.72 DRD2 (0.44) ALDH1A1CA2CA5ADRD2DRD1
SCHEMBL28470495 0.72 CA2 (0.45) ALDH1A1CA2CA5ACA12CA9
SCHEMBL7511173 0.70 MAOA (0.59) ALDH1A1CA2CA5AHPGDKDM4E
SCHEMBL23974065 0.70 MAOA (0.55) ALDH1A1CA2CA5ACA12CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996020296-A1 USE OF CHROMIUM DERIVATIVES AS BRIGHTENERS BASF AKTIENGESELLSCHAFT (DE) 1996-07-04 WO disclosed