Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8813770 | 0.82 | NOTUM (0.49) | KDM4EATMLMNANPC1RAB9A | |
| SCHEMBL8812598 | 0.82 | MEN1 (0.50) | KDM4ECNR2CNR1GAAKMT2A | |
| SCHEMBL8804281 | 0.81 | KMT2A (0.44) | KDM4EATMCNR2ACHECNR1 | |
| SCHEMBL6969602 | 0.76 | CNR2 (0.52) | KDM4ECNR2ACHECNR1GAA | |
| SCHEMBL8808537 | 0.76 | CNR2 (0.53) | CNR2ACHECNR1GAALMNA | |
| SCHEMBL8808909 | 0.75 | PTGS2 (0.55) | HTTKDM4EATMKMT2AMEN1 | |
| SCHEMBL6967696 | 0.74 | ACHE (0.44) | ATMCNR2ACHECNR1KMT2A | |
| SCHEMBL8810241 | 0.74 | LMNA (0.52) | KMT2AMEN1LMNAMAPTNPC1 | |
| SCHEMBL8806408 | 0.72 | KCNH2 (0.52) | HTTKDM4ECNR2CNR1PKM | |
| SCHEMBL6978209 | 0.69 | CNR1 (0.49) | KDM4ECNR2ACHECNR1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996004266-A2 | INDOL, INDAZOL, PYRIDOPYRROL AND PYRIDOPYRAZOL DERIVATIVES WITH ANTI-ASTHMATIC, ANTI-ALLERGIC, ANTI-INFLAMMATORY AND IMMUNOMODULATING EFFECTS | ASTA MEDICA AKTIENGESELLSCHAFT (DE) | 1996-02-15 | — | — | WO | disclosed |