Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | CTSD | P07339 | 2/20 | 0.38 |
| ▸ | APLNR | P35414 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | CBFB | Q13951 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL637824 | 0.73 | KDM4E (0.47) | NPC1ALDH1A1CTSDHPGDHSD17B10 | |
| SCHEMBL3766335 | 0.72 | BACE1 (0.43) | SMN1; SMN2NPC1ALDH1A1TP53RAB9A | |
| SCHEMBL8501500 | 0.65 | SMN1; SMN2 (0.51) | SMN1; SMN2MAPTNPC1ALDH1A1TP53 | |
| SCHEMBL10926518 | 0.64 | NPC1 (0.42) | SMN1; SMN2MAPTNPC1ALDH1A1TP53 | |
| SCHEMBL29496937 | 0.62 | SMN1; SMN2 (0.66) | SMN1; SMN2MAPTNPC1ALDH1A1TP53 | |
| SCHEMBL5463881 | 0.62 | SMN1; SMN2 (0.66) | SMN1; SMN2MAPTNPC1ALDH1A1TP53 | |
| SCHEMBL4886435 | 0.62 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPTNPC1ALDH1A1TP53 | |
| SCHEMBL6658196 | 0.62 | RAB9A (0.46) | SMN1; SMN2MAPTNPC1ALDH1A1TP53 | |
| SCHEMBL10499384 | 0.62 | CTSD (0.49) | SMN1; SMN2NPC1ALDH1A1TP53CTSD | |
| Dipyridyl SCHEMBL10393998 | 0.61 | KDM4E (0.70) | SMN1; SMN2MAPTNPC1ALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0724434-A1 | MULTIPLE UNIT TABLETED DOSAGE FORM CONTAINING PROTON PUMP INHIBITOR | Astra Aktiebolag (SE) | 1996-08-07 | — | — | EP | disclosed |
| WO-1996001625-A1 | MULTIPLE UNIT TABLETED DOSAGE FORM CONTAINING PROTON PUMP INHIBITOR | ASTRA AKTIEBOLAG (SE) | 1996-01-25 | — | — | WO | disclosed |