SCHEMBL9059717

SCHEMBL9059717

CC1=Cc2ccccc2C1C([SiH2]c1ccccc1)C1C(C)=Cc2ccccc21

nearest known ligand 0.30

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.30
TSHR P16473 1/20 0.30
ALOX12 P18054 1/20 0.30
ACHE P22303 1/20 0.30
HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27774613 0.75 HTR2A (0.34) LMNATSHRALOX12ACHEHTR2A
SCHEMBL6266174 0.75 HTR2A (0.34) LMNATSHRALOX12ACHEHTR2A
SCHEMBL12814519 0.74 LMNA (0.37) LMNATSHRALOX12ACHEHTR2A
SCHEMBL8370739 0.73 TACR1 (0.32) LMNA
SCHEMBL8861792 0.69 GPR3 (0.31) HTR2A
SCHEMBL19816957 0.69 HTR2A (0.31) HTR2A
SCHEMBL6905138 0.69 LMNA (0.32) LMNATSHRALOX12ACHEHTR2A
SCHEMBL29035817 0.69 LMNA (0.32) LMNATSHRALOX12ACHEHTR2A
SCHEMBL7936116 0.68
SCHEMBL16458893 0.68 TACR1 (0.40) LMNATSHRALOX12ACHEHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996019488-A1 A METHOD OF PREPARING HIGH PURITY RACEMIC METALLOCENE ALKYLS AND USE THEREOF EXXON CHEMICAL PATENTS INC. (US) 1996-06-27 WO disclosed