SCHEMBL905990

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Fumaric Acid SCHEMBL8151973	0.89	NPSR1 (0.46)	PDPK1JAK2CLK4FLT3DCLK1
	SCHEMBL7486071	0.88	JAK2 (0.53)	PDPK1JAK2CLK4FLT3DCLK1
	SCHEMBL905771	0.82	HTR2A (0.55)	JAK2CLK4DCLK1PRKD3MAP4K4
	SCHEMBL5987890	0.82	HTR2A (0.55)	PDPK1JAK2CLK4DCLK1PRKD3
	Hydrochloric Acid SCHEMBL5989450	0.81	HTR1A (0.54)	PDPK1JAK2CLK4DCLK1PRKD3
	SCHEMBL906084	0.79	HTR2A (0.57)	HTR2AHTR2CHTR2BHTR1A
	SCHEMBL182234	0.79	PDPK1 (0.58)	PDPK1JAK2CLK4FLT3DCLK1
	SCHEMBL30166149	0.78	SLC6A2 (0.50)	PDPK1HTR2AHTR2CHTR2BHTR1A
	SCHEMBL5989957	0.78	SLC6A2 (0.50)	PDPK1HTR2AHTR2CHTR2BHTR1A
	SCHEMBL27577588	0.77	MAPK1 (0.46)	PDPK1JAK2CLK4DCLK1PRKD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.