SCHEMBL9060204

SCHEMBL9060204

C[SiH](C)[C@]1(n2ccc(NC(=O)c3ccccc3)nc2=O)C[C@@](O)(C(C)(C)C)[C@@H](CO)O1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ABL1 P00519 1/20 0.46
RIN1 Q13671 1/20 0.46
POLB P06746 1/20 0.42
KMT2A Q03164 3/20 0.37
MEN1 O00255 2/20 0.37
P2RY6 Q15077 2/20 0.36
P2RY14 Q15391 2/20 0.36
NT5E P21589 1/20 0.36
HTR1A P08908 1/20 0.34
HTR1D P28221 1/20 0.34
HTR1B P28222 1/20 0.34
HTR1F P30939 1/20 0.34
MAPT P10636 2/20 0.33
HTT P42858 2/20 0.33
MAP3K5 Q99683 1/20 0.33
ALDH1A1 P00352 2/20 0.32
NPC1 O15118 4/20 0.32
RAB9A P51151 4/20 0.32
LMNA P02545 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30358325 0.74 ABL1 (0.38) ABL1RIN1POLBMAP3K5NPC1
SCHEMBL9060202 0.70 ABL1 (0.61) ABL1RIN1POLBKMT2AMEN1
SCHEMBL12878176 0.70 POLB (0.49) ABL1RIN1POLBKMT2AMEN1
SCHEMBL8958836 0.68 PRMT6 (0.34)
SCHEMBL235129 0.67 ABL1 (0.56) ABL1RIN1POLBKMT2AMEN1
SCHEMBL12878161 0.67 ABL1 (0.45) ABL1RIN1POLBKMT2AMEN1
SCHEMBL26136467 0.66 ABL1 (0.58) ABL1RIN1POLBKMT2AMEN1
SCHEMBL11027700 0.66 F2 (0.35) ABL1RIN1POLBKMT2AMEN1
SCHEMBL235128 0.66 ABL1 (0.56) ABL1RIN1POLBKMT2AMEN1
SCHEMBL7024939 0.66 POLB (0.44) ABL1RIN1POLBKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1996016073-A2 CODON AMIDITES AND METHOD OF USING THEM TO PRODUCE OLIGONUCLEOTIDES AND MUTAGENESIS LIBRARIES TERRAPIN TECHNOLOGIES, INC. (US) 1996-05-30 WO disclosed