Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9065654 | 0.74 | EDNRB (0.50) | EDNRAEDNRB | |
| SCHEMBL14120534 | 0.69 | CA2 (0.45) | — | |
| SCHEMBL6151353 | 0.68 | CA2 (0.51) | EDNRAEDNRB | |
| SCHEMBL1203236 | 0.68 | CA1 (0.33) | — | |
| SCHEMBL6151298 | 0.67 | CA2 (0.46) | EDNRAEDNRB | |
| SCHEMBL27466199 | 0.67 | CA2 (0.52) | EDNRAEDNRB | |
| SCHEMBL3636398 | 0.67 | NOS3 (0.48) | — | |
| SCHEMBL8724464 | 0.66 | KCNH2 (0.49) | — | |
| SCHEMBL6151081 | 0.66 | PTGS2 (0.51) | EDNRAEDNRB | |
| SCHEMBL31527719 | 0.66 | KMT2A (0.49) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699191-A1 | SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN | TEXAS BIOTECHNOLOGY CORPORATION (US) | 1996-03-06 | — | — | EP | disclosed |
| WO-1994027979-A1 | SULFONAMIDES AND DERIVATIVES THEREOF THAT MODULATE THE ACTIVITY OF ENDOTHELIN | IMMUNOPHARMACEUTICS, INC. (US) | 1994-12-08 | — | — | WO | disclosed |