Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10699442 | 0.73 | SRC (0.38) | MTNR1AMTNR1BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL10699649 | 0.73 | MTNR1A (0.34) | ALOX5MTNR1AKIF11MTNR1BFABP4 | |
| SCHEMBL8473747 | 0.72 | KIF11 (0.37) | MTNR1AKIF11MTNR1BKDM4EALDH1A1 | |
| SCHEMBL3716928 | 0.71 | ALOX5 (0.39) | MAOAMAOBALOX5ERN1MTNR1A | |
| SCHEMBL9135669 | 0.71 | ESR2 (0.38) | ALOX5KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL5506295 | 0.71 | MAOA (0.46) | MAOAMAOBALOX5ERN1MTNR1A | |
| SCHEMBL4556562 | 0.70 | HSP90AA1 (0.49) | ALOX5CYP1A2MAPTMEN1KMT2A | |
| SCHEMBL88337 | 0.70 | ITGB2 (0.42) | MAOAMAOBMTNR1AMTNR1BITGB2 | |
| SCHEMBL30054966 | 0.70 | ITGB2 (0.42) | MAOAMAOBMTNR1AMTNR1BITGB2 | |
| SCHEMBL1760592 | 0.70 | ESR2 (0.53) | MAOAALOX5KDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571442-A | SILICONE OIL, DICARBOXYLIC ACID MONOESTER EMULSIFIER, AMINOCARBOXYLIC ACID | MATSUMOTO YUSHI-SEIYAKU CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |