SCHEMBL9064636

SCHEMBL9064636

CCCCCCCCC=CCCCCCCCCN1C(=O)C=C(C)C1=O

nearest known ligand 0.65

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 5/20 0.65
FAAH O00519 5/20 0.59
PTGS1 P23219 3/20 0.49
PTGS2 P35354 3/20 0.49
TK1 P04183 1/20 0.41
TRPV1 Q8NER1 2/20 0.41
CES1 P23141 2/20 0.39
CDC25A P30304 1/20 0.39
ALDH1A1 P00352 2/20 0.38
TSHR P16473 1/20 0.38
DUSP3 P51452 1/20 0.37
PTPN7 P35236 1/20 0.37
KDM4E B2RXH2 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9064630 1.00 MGLL (0.65) MGLLFAAHPTGS1PTGS2TK1
SCHEMBL8439722 0.91 MGLL (0.58) MGLLFAAHPTGS1PTGS2CES1
SCHEMBL5970312 0.91 MGLL (0.58) MGLLFAAHPTGS1PTGS2CES1
SCHEMBL187582 0.91 MGLL (0.58) MGLLFAAHPTGS1PTGS2CES1
SCHEMBL18999087 0.91 MGLL (0.58) MGLLFAAHPTGS1PTGS2CES1
SCHEMBL4654369 0.91 MGLL (0.58) MGLLFAAHPTGS1PTGS2CES1
SCHEMBL8438883 0.91 MGLL (0.58) MGLLFAAHPTGS1PTGS2CES1
SCHEMBL8439766 0.89 MGLL (0.55) MGLLFAAHPTGS1PTGS2CES1
SCHEMBL7761775 0.84 MGLL (0.47) MGLLFAAHPTGS1PTGS2CES1
SCHEMBL907802 0.83 MGLL (0.48) MGLLFAAHPTGS1PTGS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5523360-A IMPROVES MELT-FLOW PROPERTIES AKZO NOBEL N. V. (NL) 1996-06-04 US disclosed
EP-0648240-A1 PROCESS FOR THE MODIFICATION OF POLYPHENYLENE ETHER RESIN COMPOSITIONS Akzo Nobel N.V. (NL) 1995-04-19 EP disclosed
EP-0495545-B1 Citraconimide (co)polymers and curing with anionic catalyst AKZO NOBEL NV (NL) 1994-12-28 EP disclosed
WO-1994001485-A1 PROCESS FOR THE MODIFICATION OF POLYPHENYLENE ETHER RESIN COMPOSITIONS AKZO NOBEL N.V. (NL) 1994-01-20 WO disclosed
US-5221717-A CITRACONIMIDE (CO)POLYMERS AND CURING WITH ANIONIC CATALYST AKZO N.V. (NL) 1993-06-22 US disclosed
EP-0495545-A1 Citraconimide (co)polymers and curing with anionic catalyst Akzo Nobel N.V. (NL) 1992-07-22 EP disclosed