Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 7/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | STK10 | O94804 | 7/20 | 0.35 |
| ▸ | SLK | Q9H2G2 | 7/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | CASP2 | P42575 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 3/20 | 0.34 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890003 | 0.82 | MYC (0.49) | GSK3BMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL19583334 | 0.80 | GSK3B (0.54) | GSK3BSTK10SLKCASP3CASP2 | |
| SCHEMBL3675474 | 0.75 | GSK3B (0.48) | GSK3BMEN1KMT2ASTK10SLK | |
| SCHEMBL1208344 | 0.72 | ALDH1A1 (0.39) | MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL9200511 | 0.71 | STK10 (0.43) | GSK3BSTK10SLKCASP3CASP2 | |
| SCHEMBL9204436 | 0.71 | STK10 (0.43) | GSK3BSTK10SLKCASP3CASP2 | |
| SCHEMBL10929775 | 0.71 | GSK3B (0.35) | GSK3BKMT2AALDH1A1CASP3CASP2 | |
| SCHEMBL3671511 | 0.70 | GSK3B (0.66) | GSK3BSTK10SLKGSK3A | |
| SCHEMBL9208013 | 0.68 | STK10 (0.41) | GSK3BSTK10SLKCASP3CASP2 | |
| SCHEMBL94149 | 0.67 | GSK3B (0.58) | GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523360-A | IMPROVES MELT-FLOW PROPERTIES | AKZO NOBEL N. V. (NL) | 1996-06-04 | — | — | US | disclosed |
| EP-0648240-A1 | PROCESS FOR THE MODIFICATION OF POLYPHENYLENE ETHER RESIN COMPOSITIONS | Akzo Nobel N.V. (NL) | 1995-04-19 | — | — | EP | disclosed |
| EP-0495545-B1 | Citraconimide (co)polymers and curing with anionic catalyst | AKZO NOBEL NV (NL) | 1994-12-28 | — | — | EP | disclosed |
| WO-1994001485-A1 | PROCESS FOR THE MODIFICATION OF POLYPHENYLENE ETHER RESIN COMPOSITIONS | AKZO NOBEL N.V. (NL) | 1994-01-20 | — | — | WO | disclosed |
| US-5221717-A | CITRACONIMIDE (CO)POLYMERS AND CURING WITH ANIONIC CATALYST | AKZO N.V. (NL) | 1993-06-22 | — | — | US | disclosed |
| EP-0495545-A1 | Citraconimide (co)polymers and curing with anionic catalyst | Akzo Nobel N.V. (NL) | 1992-07-22 | — | — | EP | disclosed |