Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK10 | O94804 | 6/20 | 0.41 |
| ▸ | SLK | Q9H2G2 | 6/20 | 0.41 |
| ▸ | GSK3B | P49841 | 4/20 | 0.39 |
| ▸ | HTR7 | P34969 | 2/20 | 0.39 |
| ▸ | CDC25A | P30304 | 4/20 | 0.37 |
| ▸ | CDC25B | P30305 | 4/20 | 0.37 |
| ▸ | S100A4 | P26447 | 3/20 | 0.37 |
| ▸ | MAP2K7 | O14733 | 3/20 | 0.37 |
| ▸ | CLK2 | P49760 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | CASP2 | P42575 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.35 |
| ▸ | PDE5A | O76074 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9204436 | 0.85 | STK10 (0.43) | STK10SLKGSK3BCLK2GSK3A | |
| SCHEMBL9200511 | 0.85 | STK10 (0.43) | STK10SLKGSK3BCLK2GSK3A | |
| SCHEMBL19583334 | 0.80 | GSK3B (0.54) | STK10SLKGSK3BCLK2GSK3A | |
| SCHEMBL9206390 | 0.79 | STK10 (0.46) | STK10SLKGSK3BCDC25ACDC25B | |
| SCHEMBL9204273 | 0.79 | PPOX (0.44) | STK10SLKGSK3BCLK2GSK3A | |
| SCHEMBL3675474 | 0.75 | GSK3B (0.48) | STK10SLKGSK3BCASP3CASP2 | |
| SCHEMBL3671511 | 0.70 | GSK3B (0.66) | STK10SLKGSK3BCLK2GSK3A | |
| SCHEMBL3670733 | 0.70 | NR1H2 (0.49) | — | |
| SCHEMBL8890003 | 0.69 | MYC (0.49) | GSK3BGSK3A | |
| SCHEMBL9064980 | 0.68 | GSK3B (0.39) | STK10SLKGSK3BGSK3ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0556203-B1 | (POLY)SULFIDE CONTAINING POLYCITRACONIMIDES AND POLYITACONIMIDES | AKZO NOBEL NV (NL) | 1995-10-11 | — | — | EP | disclosed |
| US-5405918-A | Accelerators for sulfur-vulcanization of rubber; tires | AKZO NOBEL N.V. (NL) | 1995-04-11 | — | — | US | disclosed |
| EP-0640114-A1 | SULFUR-VULCANIZED RUBBER COMPOSITION | Akzo Nobel N.V. (NL) | 1995-03-01 | — | — | EP | disclosed |
| WO-1993023467-A1 | SULFUR-VULCANIZED RUBBER COMPOSITION | AKZO NOBEL N.V. (NL) | 1993-11-25 | — | — | WO | disclosed |