Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 11/20 | 0.42 |
| ▸ | HTR2B | P41595 | 7/20 | 0.42 |
| ▸ | HTR2A | P28223 | 5/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13699524 | 0.79 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL164537 | 0.79 | SLC6A2 (0.59) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL3424666 | 0.78 | HTR2C (0.46) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL2463339 | 0.78 | HTR2C (0.44) | SLC6A2SLC6A4SLC6A3HTR2CHTR2B | |
| SCHEMBL2459314 | 0.78 | HTR2C (0.44) | SLC6A2SLC6A4SLC6A3HTR2CHTR2B | |
| SCHEMBL5894706 | 0.78 | SLC6A2 (0.58) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL27960525 | 0.76 | SLC6A4 (0.46) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL2110123 | 0.76 | SLC6A2 (0.46) | SLC6A2SLC6A4SLC6A3HTR2CHTR2B | |
| Methyl Alcohol SCHEMBL28137463 | 0.75 | SLC6A2 (0.55) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C | |
| SCHEMBL13134846 | 0.74 | HTR2C (0.51) | SLC6A2SLC6A4SLC6A3CYP2D6HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10745365-B2 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | PROMEGA CORPORATION (US) | 2020-08-18 | — | — | US | disclosed |
| EP-3312292-B1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | PROMEGA CORP (US) | 2019-09-25 | — | — | EP | disclosed |
| EP-1885875-B1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | PROMEGA CORP (US) | 2019-05-22 | — | — | EP | disclosed |
| US-20190031629-A1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2019-01-31 | — | — | US | disclosed |
| US-10077244-B2 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | PROMEGA CORPORATION (US) | 2018-09-18 | — | — | US | disclosed |
| EP-3312292-A1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | Promega Corporation (US) | 2018-04-25 | — | — | EP | disclosed |
| EP-2778234-B1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | PROMEGA CORP (US) | 2017-09-27 | — | — | EP | disclosed |
| EP-2545041-B1 | BIOLUMINESCENT ASSAYS USING CYANOBENZOTHIAZOLE COMPOUNDS | PROMEGA CORP (US) | 2017-08-02 | — | — | EP | disclosed |
| US-20160176830-A1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2016-06-23 | — | — | US | disclosed |
| EP-2331517-B1 | BIOLUMINESCENT ASSAYS USING CYANOBENZOTHIAZOLE COMPOUNDS | PROMEGA CORP (US) | 2016-06-08 | — | — | EP | disclosed |
| EP-2277872-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | Promega Corporation (US) | 2011-01-26 | — | — | EP | disclosed |
| EP-2272973-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | Promega Corporation (US) | 2011-01-12 | — | — | EP | disclosed |
| EP-2272972-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | Promega Corporation (US) | 2011-01-12 | — | — | EP | disclosed |
| US-20100075351-A1 | BIOLUMINESCENT DETECTION OF CYANOHYDROXY BENZOTHIAZOLE COMPOUNDS | PROMEGA CORPORATION (US) | 2010-03-25 | — | — | US | disclosed |
| WO-2010030343-A1 | BIOLUMINESCENT ASSAYS USING CYANOBENZOTHIAZOLE COMPOUNDS | PROMEGA CORPORATION (US) | 2010-03-18 | — | — | WO | disclosed |
| US-20080299593-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | PROMEGA CORPORATION (US) | 2008-12-04 | — | — | US | disclosed |
| EP-1935986-A2 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | PROMEGA CORPORATION (US) | 2008-06-25 | — | — | EP | disclosed |
| EP-1885875-A2 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | PROMEGA CORPORATION (US) | 2008-02-13 | — | — | EP | disclosed |
| US-20070015790-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2007-01-18 | — | — | US | disclosed |
| WO-2006130551-A2 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | PROMEGA CORPORATION (US) | 2006-12-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10745365-B2 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | GLB1, NOD1, PYCARD | SLC6A2 4395/4885SLC6A4 3998/4885SLC6A3 4489/4885 |
| US-10077244-B2 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | GLB1, NOD1, PYCARD | SLC6A2 4402/4885SLC6A4 3993/4885SLC6A3 4504/4885 |
| US-20080299593-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | GLB1, NOD1, PYCARD | SLC6A2 4395/4885SLC6A4 3998/4885SLC6A3 4489/4885 |
| US-20100075351-A1 | BIOLUMINESCENT DETECTION OF CYANOHYDROXY BENZOTHIAZOLE COMPOUNDS | BLVRB, BTD, BBOX1 | SLC6A2 2909/4885SLC6A4 2577/4885SLC6A3 2995/4885 |
| US-20190031629-A1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | GLB1, NOD1, PYCARD | SLC6A2 4395/4885SLC6A4 3998/4885SLC6A3 4489/4885 |
| US-20160176830-A1 | LUMINOGENIC AND FLUOROGENIC COMPOUNDS AND METHODS TO DETECT MOLECULES OR CONDITIONS | GLB1, NOD1, PYCARD | SLC6A2 4402/4885SLC6A4 3993/4885SLC6A3 4504/4885 |
| US-20070015790-A1 | Luminogenic and fluorogenic compounds and methods to detect molecules or conditions | GLB1, NOD1, PYCARD | SLC6A2 4745/4885SLC6A4 4456/4885SLC6A3 4759/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.