Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 5/20 | 0.42 |
| ▸ | SPR | P35270 | 2/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.37 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9065646 | 0.90 | ACHE (0.44) | HSD11B1SPRSLC18A3TRPA1ESR2 | |
| SCHEMBL9075391 | 0.83 | ACHE (0.53) | HSD11B1SLC18A3SIGMAR1SIRT1TRPA1 | |
| SCHEMBL9066456 | 0.83 | CRHBP (0.41) | HSD11B1SPRSLC18A3SIGMAR1SIRT1 | |
| SCHEMBL9067006 | 0.80 | ACHE (0.39) | ESR2MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL2045808 | 0.78 | ESR2 (0.52) | HSD11B1SLC18A3SIGMAR1TRPA1ESR2 | |
| SCHEMBL9803683 | 0.77 | CYP2C9 (0.33) | — | |
| SCHEMBL3817418 | 0.75 | ESR2 (0.48) | ESR2MEN1KMT2ANPC1RAB9A | |
| SCHEMBL9066299 | 0.74 | ESR2 (0.59) | HSD11B1SLC18A3SIGMAR1SIRT1TRPA1 | |
| SCHEMBL9066563 | 0.73 | TSHR (0.41) | ESR2MEN1KMT2AGAAMAPT | |
| SCHEMBL4245311 | 0.73 | ACHE (0.55) | ESR2MEN1KMT2AGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469403-B1 | High molecular weight polyester based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof | BAYER AG (DE) | 1996-02-28 | — | — | EP | disclosed |
| EP-0469404-B1 | Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof | BAYER AG (DE) | 1996-02-28 | — | — | EP | disclosed |
| EP-0469404-A2 | Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof | BAYER AG (DE) | 1992-02-05 | — | — | EP | disclosed |
| US-5034457-A | Polycarbonate for use in molding materials for laminated films and for electronics | BAYER AKTIENGESELLSCHAFT (DE) | 1991-07-23 | — | — | US | disclosed |
| US-5010163-A | Molding materials | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-23 | — | — | US | disclosed |
| EP-0374630-A2 | Polycarbonates from cyclohexylidene diphenols | BAYER AG (DE) | 1990-06-27 | — | — | EP | disclosed |