Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | HSD11B1 | P28845 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.36 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.36 |
| ▸ | RELA | Q04206 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9075391 | 0.91 | ACHE (0.53) | ACHEHSD11B1ALDH1A1ALOX15TRPA1 | |
| SCHEMBL9065627 | 0.90 | HSD11B1 (0.42) | HSD11B1GAASPRTRPA1ESR2 | |
| SCHEMBL9066299 | 0.80 | ESR2 (0.59) | ACHEHSD11B1ALDH1A1TRPA1ESR2 | |
| SCHEMBL8410883 | 0.80 | ACHE (0.60) | ACHEALDH1A1ALOX15GAAPKM | |
| SCHEMBL3192802 | 0.80 | ESR2 (0.54) | ACHEESR2ESR1 | |
| SCHEMBL9066456 | 0.77 | CRHBP (0.41) | HSD11B1SPRTRPA1ESR2ESR1 | |
| SCHEMBL297822 | 0.76 | ACHE (0.76) | ACHEALDH1A1ALOX15GAAHTT | |
| SCHEMBL10799203 | 0.76 | ACHE (0.76) | ACHEALDH1A1ALOX15GAAHTT | |
| SCHEMBL10787766 | 0.76 | ACHE (0.76) | ACHEALDH1A1ALOX15GAAHTT | |
| SCHEMBL30442737 | 0.76 | ACHE (0.76) | ACHEALDH1A1ALOX15GAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0469403-B1 | High molecular weight polyester based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof | BAYER AG (DE) | 1996-02-28 | — | — | EP | disclosed |
| EP-0469404-B1 | Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof | BAYER AG (DE) | 1996-02-28 | — | — | EP | disclosed |
| EP-0469404-A2 | Polyestercarbonates based on 1,1-bis-(4-hydroxyphenyl)-alkylcycloalkanes and thermoplastic blends thereof | BAYER AG (DE) | 1992-02-05 | — | — | EP | disclosed |
| US-5010163-A | Molding materials | BAYER AKTIENGESELLSCHAFT (DE) | 1991-04-23 | — | — | US | disclosed |
| EP-0374630-A2 | Polycarbonates from cyclohexylidene diphenols | BAYER AG (DE) | 1990-06-27 | — | — | EP | disclosed |