Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.31 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.31 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | DNM1 | Q05193 | 4/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP3 | P08254 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3310787 | 0.76 | ALDH1A1 (0.41) | ALDH1A1CA12CA1CA9DNM1 | |
| SCHEMBL9065367 | 0.76 | CYP1A2 (0.36) | GABBR2GABRR1GABBR1CYP1A2KMT2A | |
| SCHEMBL9624015 | 0.69 | DNM1 (0.43) | ALDH1A1DNM1TSHR | |
| SCHEMBL15224212 | 0.66 | EPHX2 (0.49) | ALDH1A1GABBR2GABRR1GABBR1CYP1A2 | |
| SCHEMBL5253602 | 0.65 | CA12 (0.43) | ALDH1A1CA12CA1CA9TSHR | |
| SCHEMBL9424278 | 0.65 | ALDH1A1 (0.46) | ALDH1A1CA12CA1CA9CYP1A2 | |
| Hexane SCHEMBL11414372 | 0.64 | ALDH1A1 (0.55) | ALDH1A1MEN1KMT2ATSHR | |
| SCHEMBL9792595 | 0.64 | ALDH1A1 (0.33) | ALDH1A1TSHR | |
| SCHEMBL28276404 | 0.64 | DNM1 (0.55) | ALDH1A1GABBR2GABRR1GABBR1DNM1 | |
| SCHEMBL10388723 | 0.64 | CA1 (0.52) | ALDH1A1CA12CA1CA9TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591622-B1 | Room-temperature curable polyorganosiloxane composition | TOSHIBA SILICONE (JP) | 1996-11-20 | — | — | EP | disclosed |
| US-5371164-A | Blend with a polysilazane | TOSHIBA SILICONE CO., LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| EP-0591622-A1 | Room-temperature curable polyorganosiloxane composition | TOSHIBA SILICONE CO., LTD. (JP) | 1994-04-13 | — | — | EP | disclosed |