Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.36 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.36 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9065643 | 0.76 | ALDH1A1 (0.33) | CYP1A2GABBR2TSHRGABRR1KMT2A | |
| SCHEMBL9120072 | 0.71 | CHRM2 (0.38) | LMNATSHRBLMKMT2ACHRM2 | |
| SCHEMBL407237 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL3650642 | 0.65 | ALDH1A1 (0.58) | CYP1A2GABRR3GABRPGABRDHDAC3 | |
| SCHEMBL9810877 | 0.63 | ALDH1A1 (0.35) | TSHRNFKB1 | |
| SCHEMBL3316208 | 0.63 | ALDH1A1 (0.35) | TSHRNFKB1 | |
| SCHEMBL2490154 | 0.62 | CHRNB2 (0.48) | CYP1A2TSHRKMT2APAOX | |
| SCHEMBL24029800 | 0.62 | ALDH1A1 (0.30) | TSHRCHRM2 | |
| SCHEMBL9119054 | 0.62 | DNM1 (0.33) | TSHRKMT2ANFKB1 | |
| Acetone SCHEMBL28554619 | 0.62 | PAOX (0.43) | CYP1A2GABRR3GABRPGABRDHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591622-B1 | Room-temperature curable polyorganosiloxane composition | TOSHIBA SILICONE (JP) | 1996-11-20 | — | — | EP | disclosed |
| US-5371164-A | Blend with a polysilazane | TOSHIBA SILICONE CO., LTD. (JP) | 1994-12-06 | — | — | US | disclosed |
| EP-0591622-A1 | Room-temperature curable polyorganosiloxane composition | TOSHIBA SILICONE CO., LTD. (JP) | 1994-04-13 | — | — | EP | disclosed |