Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 7/20 | 0.35 |
| ▸ | MAOB | P27338 | 7/20 | 0.34 |
| ▸ | BRD4 | O60885 | 4/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.34 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6205578 | 0.91 | MAOB (0.40) | SMN1; SMN2MAOAMAOBBRD4CREBBP | |
| SCHEMBL2783537 | 0.71 | ALDH1A1 (0.43) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL9667808 | 0.64 | ALDH1A1 (0.38) | SMN1; SMN2MAOAMAOBALDH1A1 | |
| SCHEMBL1338840 | 0.63 | ALDH1A1 (0.47) | SMN1; SMN2ALDH1A1GRM2 | |
| SCHEMBL13934519 | 0.62 | MEN1 (0.45) | SMN1; SMN2ALDH1A1GRM2KDM4E | |
| SCHEMBL6136318 | 0.61 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL10522808 | 0.61 | KCNH2 (0.38) | SMN1; SMN2ALDH1A1 | |
| SCHEMBL35509 | 0.61 | — | — | |
| SCHEMBL432483 | 0.61 | — | — | |
| SCHEMBL374192 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0737231-A1 | THERMAL STABILIZED RESIN COMPOSITIONS | KOLON INDUSTRIES, INC. (KR) | 1996-10-16 | — | — | EP | disclosed |
| WO-1995018181-A1 | THERMAL STABILIZED RESIN COMPOSITIONS | KOLON INDUSTRIES, INC. (KR) | 1995-07-06 | — | — | WO | disclosed |