Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.40 |
| ▸ | MAOA | P21397 | 4/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.38 |
| ▸ | USP1 | O94782 | 1/20 | 0.38 |
| ▸ | WDR48 | Q8TAF3 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9065988 | 0.91 | SMN1; SMN2 (0.41) | MAOBMAOAALDH1A1BRD4CREBBP | |
| SCHEMBL1338840 | 0.74 | ALDH1A1 (0.47) | KMT2AALDH1A1MEN1USP1WDR48 | |
| SCHEMBL9319835 | 0.71 | ALDH1A1 (0.51) | KMT2ARAB9AALDH1A1NPC1MEN1 | |
| SCHEMBL84708 | 0.68 | KMT2A (0.44) | MAOBKMT2ARAB9AALDH1A1GAA | |
| SCHEMBL6365734 | 0.66 | MAOB (0.43) | MAOBKMT2ARAB9AALDH1A1GAA | |
| SCHEMBL4046759 | 0.66 | USP1 (0.38) | KMT2ARAB9AALDH1A1GAAMAPT | |
| SCHEMBL2783537 | 0.63 | ALDH1A1 (0.43) | ALDH1A1SMN1; SMN2HPGD | |
| SCHEMBL28574856 | 0.63 | NOS1 (0.39) | MAOBKMT2ARAB9AALDH1A1GAA | |
| SCHEMBL4054286 | 0.62 | SMN1; SMN2 (0.44) | KMT2ARAB9AALDH1A1GAAMAPT | |
| SCHEMBL2782902 | 0.62 | ALDH1A1 (0.42) | ALDH1A1NPC1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1461315-A4 | CATALYTIC CARBONYLATION OF THREE AND FOUR MEMBERED HETEROCYCLES | CORNELL RES FOUNDATION INC (US) | 2005-06-01 | — | — | EP | disclosed |
| EP-1461315-A2 | CATALYTIC CARBONYLATION OF THREE AND FOUR MEMBERED HETEROCYCLES | CORNELL RESEARCH FOUNDATION, INC. (US) | 2004-09-29 | — | — | EP | disclosed |
| WO-2003050154-A2 | CATALYTIC CARBONYLATION OF THREE AND FOUR MEMBERED HETEROCYCLES | CORNELL RESEARCH FOUNDATION, INC. (US) | 2003-06-19 | — | — | WO | disclosed |