Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.38 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.38 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10891795 | 1.00 | FAAH (0.41) | FAAHSMN1; SMN2SLC6A5ITGB3ITGA2B | |
| SCHEMBL5122363 | 0.94 | ITGB3 (0.40) | FAAHSMN1; SMN2SLC6A5ITGB3ITGA2B | |
| SCHEMBL5131032 | 0.94 | ITGB3 (0.40) | FAAHSMN1; SMN2SLC6A5ITGB3ITGA2B | |
| SCHEMBL5122365 | 0.94 | ITGB3 (0.40) | FAAHSMN1; SMN2SLC6A5ITGB3ITGA2B | |
| SCHEMBL7771214 | 0.81 | PLA2G2A (0.50) | SMN1; SMN2ACE2CA2 | |
| SCHEMBL7771220 | 0.81 | PLA2G2A (0.50) | SMN1; SMN2ACE2CA2 | |
| SCHEMBL2435695 | 0.80 | ADAMTS4 (0.42) | ACE2CA2 | |
| SCHEMBL29194944 | 0.78 | HTT (0.34) | FAAHSMN1; SMN2SLC6A5ITGB3ITGA2B | |
| SCHEMBL8906669 | 0.78 | CA2 (0.44) | FAAHCA2 | |
| SCHEMBL6574037 | 0.78 | CA1 (0.37) | ITGB3ITGA2BCA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516936-A | TREATMENT OF NEUROLOGICAL DISORDERS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1996-05-14 | — | — | US | disclosed |
| EP-0581907-A4 | — | — | 1994-04-06 | — | — | EP | disclosed |
| EP-0581907-A1 | INHIBITORS OF KYNURENINASE | THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1994-02-09 | — | — | EP | disclosed |
| WO-1992018003-A1 | INHIBITORS OF KYNURENINASE | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1992-10-29 | — | — | WO | disclosed |
| US-4632931-A | ANTICOAGULANTS, BRONCHODILATOR AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1986-12-30 | — | — | US | disclosed |