Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR139 | Q6DWJ6 | 2/20 | 0.34 |
| ▸ | MME | P08473 | 6/20 | 0.34 |
| ▸ | ACE | P12821 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.33 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.33 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.33 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.33 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.33 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.33 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.33 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.33 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.33 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.33 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6811299 | 0.81 | MTNR1A (0.35) | GPR139KMT2AMEN1ALDH1A1HPGD | |
| SCHEMBL9067654 | 0.75 | GPR139 (0.47) | GPR139MMEACEKMT2AMEN1 | |
| SCHEMBL9067650 | 0.70 | ACE (0.40) | GPR139MMEACEKMT2AMEN1 | |
| SCHEMBL1358406 | 0.67 | MME (0.45) | MMEACEKMT2AMEN1MMP8 | |
| SCHEMBL29758904 | 0.67 | ALDH1A1 (0.47) | MMEACEALDH1A1MAPTECE1 | |
| SCHEMBL10940525 | 0.65 | CTSL (0.46) | MMEACEKMT2AMEN1ALDH1A1 | |
| SCHEMBL30123547 | 0.65 | CTSC (0.52) | MMEACEKMT2AMEN1OPRD1 | |
| SCHEMBL10940533 | 0.65 | CTSL (0.46) | MMEACEKMT2AMEN1ALDH1A1 | |
| SCHEMBL10505335 | 0.65 | MME (0.48) | GPR139MMEACEKMT2AMEN1 | |
| SCHEMBL10939141 | 0.65 | MME (0.45) | MMEACEKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534497-A | RADIOPHARMACEUTICALS; MEDICAL DIAGNOSIS | MALLINCKRODT MEDICAL, INC. (US) | 1996-07-09 | — | — | US | disclosed |