Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | CTSK | P43235 | 7/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.32 |
| ▸ | CTSL | P07711 | 2/20 | 0.31 |
| ▸ | CTSS | P25774 | 2/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | REN | P00797 | 3/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9069940 | 0.83 | CTSK (0.34) | CTSKPSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9067940 | 0.78 | MMP1 (0.32) | MMP3CTSKPSEN1PSEN2APH1B | |
| SCHEMBL9073693 | 0.74 | PSEN1 (0.32) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9068424 | 0.70 | MMP1 (0.39) | MMP3CTSKPSEN1PSEN2APH1B | |
| SCHEMBL19961863 | 0.65 | SMN1; SMN2 (0.48) | MAPK1 | |
| SCHEMBL9068586 | 0.64 | MMP1 (0.32) | MMP3CTSL | |
| SCHEMBL9070551 | 0.62 | MMP1 (0.34) | MMP3CTSLCTSD | |
| SCHEMBL7475849 | 0.61 | BACE1 (0.37) | MMP3CTSD | |
| SCHEMBL21602301 | 0.60 | LMNA (0.44) | CTSKCTSS | |
| SCHEMBL20333385 | 0.60 | MMP8 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571793-A | COMBATTING ENDOPARASITES IN HUMANS OR ANIMALS BY ADMINISTERING PEPTIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-05 | — | — | US | claimed |
| US-5571793-A | COMBATTING ENDOPARASITES IN HUMANS OR ANIMALS BY ADMINISTERING PEPTIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-05 | — | — | US | disclosed |