Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 3/20 | 0.32 |
| ▸ | MMP3 | P08254 | 3/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 4/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 4/20 | 0.31 |
| ▸ | APH1B | Q8WW43 | 4/20 | 0.31 |
| ▸ | NCSTN | Q92542 | 4/20 | 0.31 |
| ▸ | APH1A | Q96BI3 | 4/20 | 0.31 |
| ▸ | PSENEN | Q9NZ42 | 4/20 | 0.31 |
| ▸ | BACE1 | P56817 | 3/20 | 0.31 |
| ▸ | CTSD | P07339 | 2/20 | 0.31 |
| ▸ | CTSE | P14091 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP7 | P09237 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | MMP8 | P22894 | 1/20 | 0.31 |
| ▸ | CTSL | P07711 | 1/20 | 0.31 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9073693 | 0.95 | PSEN1 (0.32) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9069940 | 0.86 | CTSK (0.34) | PSEN1PSEN2APH1BNCSTNAPH1A | |
| SCHEMBL9068424 | 0.85 | MMP1 (0.39) | MMP1MMP3PSEN1PSEN2APH1B | |
| SCHEMBL9070551 | 0.85 | MMP1 (0.34) | MMP1MMP3BACE1CTSDCTSE | |
| SCHEMBL8708141 | 0.78 | ALDH1A1 (0.36) | MMP1MMP3PSEN1PSEN2APH1B | |
| SCHEMBL9067752 | 0.78 | MMP3 (0.35) | MMP3PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL8710905 | 0.76 | MMP1 (0.35) | MMP1MMP3BACE1CTSDCTSE | |
| SCHEMBL8713431 | 0.67 | MMP1 (0.44) | MMP1MMP3MMP2MMP7MMP9 | |
| SCHEMBL9068717 | 0.66 | HPGD (0.33) | MMP1MMP3PSEN1PSEN2APH1B | |
| SCHEMBL19961863 | 0.66 | SMN1; SMN2 (0.48) | MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571793-A | COMBATTING ENDOPARASITES IN HUMANS OR ANIMALS BY ADMINISTERING PEPTIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-11-05 | — | — | US | claimed |
| US-5525591-A | HUMAN OR VETERINARY MEDICINE | BAYER AKTIENGESELLSCHAFT (DE) | 1996-06-11 | — | — | US | disclosed |