SCHEMBL9067792

SCHEMBL9067792

COC(=O)c1ccc(C(=O)O)cc1C1CCCCC1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMO O15229 1/20 0.47
ALDH1A1 P00352 8/20 0.44
KDM4E B2RXH2 5/20 0.44
HPGD P15428 3/20 0.44
GAA P10253 3/20 0.42
ATM Q13315 2/20 0.42
MAPT P10636 2/20 0.42
GLA P06280 1/20 0.42
CASP1 P29466 1/20 0.42
CASP7 P55210 1/20 0.42
HSD17B10 Q99714 1/20 0.42
PPM1D O15297 2/20 0.42
SMN1; SMN2 Q16637 2/20 0.41
NPSR1 Q6W5P4 1/20 0.41
NPC1 O15118 1/20 0.41
EPHX2 P34913 1/20 0.41
PTGDR2 Q9Y5Y4 3/20 0.40
CYP2C19 P33261 1/20 0.40
PTGDR Q13258 1/20 0.40
CREBBP Q92793 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1775666 0.91 ALDH1A1 (0.52) ALDH1A1KDM4EHPGDGAAATM
Methyl Alcohol SCHEMBL31596316 0.85 KMO (0.51) KMOCAMKK2
SCHEMBL30952631 0.85 KMO (0.54) KMOCAMKK2
SCHEMBL448284 0.85 KMO (0.54) KMOCAMKK2
SCHEMBL28791941 0.84 KMO (0.46) KMOALDH1A1KDM4EGAAMAPT
SCHEMBL27576533 0.83 KMO (0.44) KMOALDH1A1KDM4EGAAMAPT
SCHEMBL28170978 0.83 CAMKK2 (0.52) KMOKDM4ECAMKK2
SCHEMBL28682072 0.82 CA12 (0.54) ALDH1A1KDM4EHPGDGAAMAPT
SCHEMBL2445552 0.80 CAMKK2 (0.49) KMOALDH1A1KDM4ECAMKK2
SCHEMBL29470084 0.80 CAMKK2 (0.49) KMOALDH1A1KDM4ECAMKK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0679203-A4 POLYESTER MONOFILAMENTS EXTRUDED FROM A POLYESTER RESIN BLEND. SHAKESPEARE CO (US) 1996-01-17 EP disclosed
EP-0679203-A1 POLYESTER MONOFILAMENTS EXTRUDED FROM A POLYESTER RESIN BLEND SHAKESPEARE COMPANY (US) 1995-11-02 EP disclosed
WO-1995013423-A1 POLYESTER MONOFILAMENTS EXTRUDED FROM A POLYESTER RESIN BLEND SHAKESPEARE COMPANY (US) 1995-05-18 WO disclosed