Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7559465 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL7766701 | 0.76 | — | — | |
| Hydrochloric Acid SCHEMBL5165528 | 0.75 | CYP11B1 (0.35) | — | |
| SCHEMBL1453949 | 0.75 | CYP11B1 (0.33) | — | |
| Hydrochloric Acid SCHEMBL9068323 | 0.74 | PNMT (0.32) | — | |
| SCHEMBL29287776 | 0.74 | PSMB5 (0.34) | BCHEACHE | |
| SCHEMBL1453940 | 0.72 | GPR3 (0.33) | LMNA | |
| SCHEMBL7031827 | 0.72 | CRHR1 (0.32) | — | |
| SCHEMBL28289412 | 0.71 | CYP3A4 (0.41) | BCHEACHELMNA | |
| Hydrochloric Acid SCHEMBL27932999 | 0.71 | CYP3A4 (0.33) | BCHEACHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0745607-A2 | Metallocene preparation and use | PHILLIPS PETROLEUM COMPANY (US) | 1996-12-04 | — | — | EP | claimed |