Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | FPR2 | P25090 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MME | P08473 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.44 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.44 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7283853 | 1.00 | ALDH1A1 (0.53) | ALDH1A1HSD17B10HRH3POLBFPR2 | |
| SCHEMBL7282932 | 1.00 | ALDH1A1 (0.53) | ALDH1A1HSD17B10HRH3POLBFPR2 | |
| SCHEMBL7283028 | 0.89 | TACR2 (0.54) | ALDH1A1HSD17B10POLBKMT2AMEN1 | |
| SCHEMBL7279559 | 0.89 | POLB (0.46) | ALDH1A1HSD17B10POLBFPR2KMT2A | |
| SCHEMBL9069239 | 0.88 | OPRK1 (0.48) | ALDH1A1HRH3POLBTDP1 | |
| SCHEMBL7284790 | 0.88 | OPRK1 (0.48) | ALDH1A1HRH3POLBTDP1 | |
| SCHEMBL7273374 | 0.88 | OPRK1 (0.48) | ALDH1A1HRH3POLBTDP1 | |
| SCHEMBL7275716 | 0.86 | KMT2A (0.56) | ALDH1A1HSD17B10HRH3POLBKMT2A | |
| SCHEMBL7271561 | 0.82 | ACE (0.50) | FPR2MMELMNATDP1PSMB1 | |
| SCHEMBL6895655 | 0.80 | ITGA4 (0.54) | MMELMNAPSMB1PSMB5PSMB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5491132-A | HYPOTENSIVE AGENT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-13 | — | — | US | disclosed |