Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | AMPD2 | Q01433 | 3/20 | 0.41 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13925442 | 0.89 | ALDH1A1 (0.48) | ALDH1A1NPSR1LMNATSHRUSP2 | |
| SCHEMBL15702659 | 0.86 | ALDH1A1 (0.48) | ALDH1A1NPSR1LMNATSHRUSP2 | |
| SCHEMBL15702596 | 0.83 | MDM2 (0.47) | ALDH1A1NPSR1LMNATSHRUSP2 | |
| SCHEMBL7879104 | 0.83 | LMNA (0.54) | ALDH1A1NPSR1LMNATSHRUSP2 | |
| SCHEMBL11076148 | 0.83 | LMNA (0.54) | ALDH1A1NPSR1LMNATSHRUSP2 | |
| SCHEMBL9166728 | 0.81 | LMNA (0.53) | ALDH1A1NPSR1LMNATSHRUSP2 | |
| SCHEMBL29638140 | 0.81 | LMNA (0.53) | ALDH1A1NPSR1LMNATSHRUSP2 | |
| SCHEMBL21160461 | 0.77 | LMNA (0.53) | ALDH1A1NPSR1LMNATSHRUSP2 | |
| SCHEMBL9163104 | 0.77 | AMPD2 (0.37) | ALDH1A1NPSR1LMNATSHRUSP2 | |
| SCHEMBL9074053 | 0.76 | LMNA (0.48) | ALDH1A1NPSR1LMNATSHRUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547727-A | RADIATION TRANSPARENT SUBSTRATE WITH RECORDING AND REFLECTION LAYERS WITH DYES OF CATIONIC AZOCYANINE DYES | EASTMAN KODAK COMPANY (US) | 1996-08-20 | — | — | US | claimed |
| EP-0717402-A2 | Optical recording elements having recording layers containing cationic azo dyes | EASTMAN KODAK COMPANY (US) | 1996-06-19 | — | — | EP | claimed |
| US-20090036484-A1 | Use of Unsaturated Quionoline or Naphtalene Derivatives as Medicaments | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | US | disclosed |
| US-20090036484-A1 | Use of Unsaturated Quionoline or Naphtalene Derivatives as Medicaments | ASTRAZENECA AB (SE) | 2009-02-05 | — | — | US | disclosed |
| US-5547727-A | RADIATION TRANSPARENT SUBSTRATE WITH RECORDING AND REFLECTION LAYERS WITH DYES OF CATIONIC AZOCYANINE DYES | EASTMAN KODAK COMPANY (US) | 1996-08-20 | — | — | US | disclosed |
| EP-0717402-A2 | Optical recording elements having recording layers containing cationic azo dyes | EASTMAN KODAK COMPANY (US) | 1996-06-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036484-A1 | Use of Unsaturated Quionoline or Naphtalene Derivatives as Medicaments | NR3C1, NR3C2, NR5A1 | ALDH1A1 1475/4885NPSR1 33/4885LMNA 1363/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.