Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29219248 | 0.80 | DGAT1 (0.31) | DGAT1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL28505878 | 0.79 | CES1 (0.34) | — | |
| SCHEMBL12040169 | 0.79 | DGAT1 (0.34) | DGAT1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL29062598 | 0.77 | DGAT1 (0.33) | DGAT1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL28859003 | 0.76 | CES2 (0.38) | — | |
| SCHEMBL9220667 | 0.75 | THRB (0.38) | — | |
| SCHEMBL29062585 | 0.74 | APP (0.32) | DGAT1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL2802412 | 0.73 | HDAC6 (0.37) | DGAT1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL644646 | 0.72 | TSHR (0.45) | DGAT1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL3558406 | 0.70 | EPHX2 (0.39) | DGAT1HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5587499-A | SIMPLE, EFFICIENT | ELF ATOCHEM S.A. (FR) | 1996-12-24 | — | — | US | disclosed |
| US-5457172-A | An alkoxycarbonylalkylthio(or sulfone or sulfoxide) alkyl acrylate monomer; homo- and copolymers; molding materials; castings; binders; coating vehicles | ELF ATOCHEM S.A. (FR) | 1995-10-10 | — | — | US | disclosed |