Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.38 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2666926 | 0.81 | MAOA (0.44) | HTR2CMAOAMAOBHTR2AHTR2B | |
| SCHEMBL2666743 | 0.76 | PKM (0.41) | HTR2CMAOAMAOBHTR2AHTR2B | |
| SCHEMBL2667069 | 0.74 | DRD2 (0.39) | HTR2CHTR2AHTR2BADRA1AADRA1D | |
| SCHEMBL2666963 | 0.74 | POLB (0.50) | MAOAMAOBMEN1KMT2APKM | |
| SCHEMBL9072147 | 0.74 | DHFR (0.51) | MEN1KMT2APKMALDH1A1GAA | |
| SCHEMBL2667068 | 0.73 | HTR2C (0.40) | HTR2CMAOAMAOBHTR2AHTR2B | |
| SCHEMBL9072004 | 0.72 | MAOA (0.51) | HTR2CMAOAMAOBHTR2BHSP90AA1 | |
| SCHEMBL9071989 | 0.71 | L3MBTL1 (0.43) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL2667043 | 0.71 | CXCL12 (0.60) | MAOAMAOBHTR2BHSP90AA1HSP90AB1 | |
| SCHEMBL9072000 | 0.70 | HTR7 (0.40) | ADRA1AADRA1DMAP1LC3BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007061923-A2 | GLUCOKINASE ACTIVATORS | TAKEDA SAN DIEGO, INC. (US) | 2007-05-31 | — | — | WO | disclosed |