Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.66 |
| ▸ | ALDH5A1 | P51649 | 2/20 | 0.57 |
| ▸ | ABAT | P80404 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.57 |
| ▸ | FDPS | P14324 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.48 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3684285 | 0.86 | ALDH1A1 (0.70) | ALDH1A1ALDH5A1ABATHPGDTRIM24 | |
| SCHEMBL359491 | 0.85 | ALDH1A1 (0.68) | ALDH1A1ALDH5A1ABATHPGDTRIM24 | |
| SCHEMBL972755 | 0.83 | ALDH1A1 (0.76) | ALDH1A1ALDH5A1ABATHPGDTRIM24 | |
| SCHEMBL19782689 | 0.83 | ALDH1A1 (0.66) | ALDH1A1ALDH5A1ABATHPGDTRIM24 | |
| SCHEMBL2890759 | 0.82 | ALDH1A1 (0.73) | ALDH1A1ALDH5A1ABATHPGDTRIM24 | |
| SCHEMBL1515911 | 0.82 | ALDH1A1 (0.69) | ALDH1A1ALDH5A1ABATHPGDTRIM24 | |
| SCHEMBL17782945 | 0.81 | ALDH1A1 (0.72) | ALDH1A1ALDH5A1ABATHPGDTRIM24 | |
| SCHEMBL14323012 | 0.81 | ALDH1A1 (0.71) | ALDH1A1ALDH5A1ABATHPGDTRIM24 | |
| SCHEMBL1098158 | 0.81 | ALDH1A1 (0.67) | ALDH1A1ALDH5A1ABATHPGDTRIM24 | |
| SCHEMBL1238727 | 0.80 | FDPS (0.50) | ALDH1A1ALDH5A1ABATHPGDTRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999001423-A1 | GLUCAGON ANTAGONISTS/INVERSE AGONISTS | NOVO NORDISK A/S (DK) | 1999-01-14 | — | — | WO | disclosed |