Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1408568 | 0.94 | ALDH1A1 (0.44) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL234461 | 0.80 | ALDH1A1 (0.58) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL27660168 | 0.74 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL24385153 | 0.71 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL27251960 | 0.71 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL10887099 | 0.71 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL712641 | 0.69 | — | — | |
| SCHEMBL31217749 | 0.69 | ALDH1A1 (0.38) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL16712211 | 0.67 | ALDH1A1 (0.41) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL14396321 | 0.67 | ENPP2 (0.48) | ALDH1A1HSD17B10TSHRTP53MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0448391-B1 | Process for making controlled uniform-sized polymer particles | ROHM & HAAS (US) | 1996-05-22 | — | — | EP | disclosed |
| EP-0342283-B1 | THERMOPLASTIC AND THERMOSET POLYMER COMPOSITIONS | ROHM AND HAAS COMPANY (US) | 1993-02-17 | — | — | EP | disclosed |
| US-5147937-A | PROCESS FOR MAKING CONTROLLED, UNIFORM-SIZED PARTICLES IN THE 1 TO 50 MICROMETER RANGE | ROHM AND HAAS COMPANY (US) | 1992-09-15 | — | — | US | disclosed |
| EP-0448391-A2 | Process for making controlled uniform-sized polymer particles | ROHM AND HAAS COMPANY (US) | 1991-09-25 | — | — | EP | disclosed |