Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 known ✓ | P00915 | 1/20 | 0.36 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | CASP3 | P42574 | 1/20 | 0.31 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.31 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9073535 | 0.94 | ALDH1A1 (0.44) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL234461 | 0.80 | ALDH1A1 (0.58) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL27660168 | 0.74 | ALDH1A1 (0.52) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| Hydroquinone SCHEMBL20526059 | 0.73 | CA1 (0.44) | CA1CA2 | |
| SCHEMBL24385153 | 0.71 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL27251960 | 0.71 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL10887099 | 0.71 | ALDH1A1 (0.50) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL712641 | 0.69 | — | — | |
| SCHEMBL31217749 | 0.69 | ALDH1A1 (0.38) | ALDH1A1HSD17B10TSHRTP53MAPK1 | |
| SCHEMBL28143286 | 0.69 | CA2 (0.56) | ALDH1A1HSD17B10CA1CA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2295471-B1 | Method for making swellable particles | ROHM & HAAS (US) | 2019-10-23 | — | — | EP | disclosed |
| EP-1764374-B1 | Method for making swellable particles | ROHM & HAAS (US) | 2019-05-01 | — | — | EP | disclosed |
| EP-2295472-B1 | Swellable particles | ROHM & HAAS (US) | 2017-06-28 | — | — | EP | disclosed |
| EP-2295473-B1 | Swellable particles | ROHM & HAAS (US) | 2016-12-28 | — | — | EP | disclosed |
| EP-2295471-A1 | Swellable particles | Rohm and Haas Company (US) | 2011-03-16 | — | — | EP | disclosed |
| EP-2295472-A1 | Swellable particles | Rohm and Haas Company (US) | 2011-03-16 | — | — | EP | disclosed |
| EP-2295473-A1 | Swellable particles | Rohm and Haas Company (US) | 2011-03-16 | — | — | EP | disclosed |
| US-20070066761-A1 | Swellable particles | ROHM AND HAAS COMPANY | 2007-03-22 | — | — | US | disclosed |
| EP-1764374-A1 | Swellable particles | Rohm and Haas Company (US) | 2007-03-21 | — | — | EP | disclosed |
| EP-0821017-B1 | Liquid crystal displays containing spacers and methods for producing the spacer | ROHM & HAAS (US) | 2002-10-09 | — | — | EP | disclosed |
| US-6031051-A | Liquid crystal displays containing spacers and methods for producing the spacer | ROHM AND HAAS COMPANY (US) | 2000-02-29 | — | — | US | disclosed |
| US-5846657-A | Liquid crystal displays containing spacers and methods for producing the spacer | ROHM AND HAAS COMPANY (US) | 1998-12-08 | — | — | US | disclosed |
| EP-0821017-A2 | Liquid crystal displays containing spacers and methods for producing the spacer | ROHM AND HAAS COMPANY (US) | 1998-01-28 | — | — | EP | disclosed |
| EP-0536935-B1 | Co-microagglomeration of emulsion polymers | ROHM & HAAS (US) | 1996-05-29 | — | — | EP | disclosed |
| US-5442012-A | Process for making encapsulated micro-agglomerated core/shell additives for PVC blends | ROHM AND HAAS COMPANY (US) | 1995-08-15 | — | — | US | disclosed |
| US-5276092-A | Encapsulated micro-agglomerated core/shell additives in poly(vinyl chloride) blends | ROHM AND HAAS COMPANY (US) | 1994-01-04 | — | — | US | disclosed |
| US-5221713-A | CO-MICROAGGLOMERATION OF EMULSION POLYMERS (ENCAPSULATED CORE/SHELL ADDITIVES FOR PVC) | ROHM AND HAAS COMPANY (US) | 1993-06-22 | — | — | US | disclosed |
| EP-0536935-A1 | Co-microagglomeration of emulsion polymers | ROHM AND HAAS COMPANY (US) | 1993-04-14 | — | — | EP | disclosed |
| EP-0020065-B1 | A METHOD FOR INHIBITING THE POLYMERIZATION OF ACRYLIC MONOMERS IN AQUEOUS LIQUIDS CONTAINING THEM | ROHM AND HAAS COMPANY (US) | 1983-02-23 | — | — | EP | disclosed |
| EP-0020065-A1 | A method for inhibiting the polymerization of acrylic monomers in aqueous liquids containing them | ROHM AND HAAS COMPANY (US) | 1980-12-10 | — | — | EP | disclosed |