Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.66 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.58 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL9077392 | 0.91 | KDM4E (0.58) | SIGMAR1MEN1KMT2AKDM4EALDH1A1 | |
| Oxalic Acid SCHEMBL9077245 | 0.90 | MEN1 (0.57) | SIGMAR1MEN1KMT2AKDM4EALDH1A1 | |
| Oxalic Acid SCHEMBL9075949 | 0.85 | HTR1A (0.55) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| Oxalic Acid SCHEMBL9077499 | 0.79 | SIGMAR1 (1.00) | SIGMAR1 | |
| SCHEMBL9076740 | 0.79 | HPGD (0.53) | SCN9A | |
| SCHEMBL8733917 | 0.78 | SCN9A (0.53) | SCN9A | |
| Oxalic Acid SCHEMBL8728762 | 0.77 | BCHE (0.61) | — | |
| SCHEMBL11569134 | 0.76 | ALDH1A1 (0.63) | SIGMAR1SCN9AMEN1KMT2AKDM4E | |
| Oxalic Acid SCHEMBL8198057 | 0.75 | BCHE (0.64) | — | |
| SCHEMBL14970725 | 0.75 | POLB (0.76) | HRH3MEN1KMT2APOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5495046-A | PSYCHOLOGICAL DISORDERS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1996-02-27 | — | — | US | disclosed |
| EP-0641766-A1 | ALKOXYPHENYLALKYLAMINE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-03-08 | — | — | EP | disclosed |